Hierarchically oriented organization in supramolecular peptide crystals

doi:10.1038/s41570-019-0129-8

	Hierarchically oriented organization in supramolecular peptide crystals
	Yuan, Chengqian 2; Ji, Wei 3; Xing, Ruirui 2; Li, Junbai 4,5; Gazit, Ehud 3,6; Yan, Xuehai 1,2,5
刊名	NATURE REVIEWS CHEMISTRY
	2019-10-01
卷号	3 期号:10 页码:567-588
DOI	10.1038/s41570-019-0129-8
英文摘要	Hierarchical self-assembly and crystallization with long-range ordered spatial arrangement is ubiquitous in nature and plays an essential role in the regulation of structures and biological functions. Inspired by the multiscale hierarchical structures in biology, tremendous efforts have been devoted to the understanding of hierarchical self-assembly and crystallization of biomolecules such as peptides and amino acids. Understanding the fundamental mechanisms underlying the construction and organization of multiscale architectures is crucial for the design and fabrication of complex functional systems with long-range alignment of molecules. This Review summarizes the typical examples for hierarchically oriented organization of peptide self-assembly and discusses the thermodynamic and kinetic mechanisms that are responsible for this specific hierarchical organization. Most importantly, we propose the concept of hierarchically oriented organization for self-assembling peptide crystals, distinct from the traditional growth mechanism of supramolecular polymerization and crystallization based on the Ostwald ripening rule. Finally, we assess critical challenges and highlight future directions towards the mechanistic understanding and versatile application of the hierarchically oriented organization mechanism.
资助项目	National Natural Science Foundation of China[21522307] ; National Natural Science Foundation of China[21802143] ; National Natural Science Foundation of China[21802144] ; National Natural Science Fund BRICS STI Framework Programme[51861145304] ; Innovation Research Community Science Fund[21821005] ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (CAS)[QYZDB-SSW-JSC034] ; European Research Council under the European Union Horizon 2020 research and innovation programme (BISON)[694426]
WOS关键词	CYCLIC DIPEPTIDE DERIVATIVES ; COMPLEX HELICAL COLUMNS ; SELF-ORGANIZATION ; PERYLENE BISIMIDE ; STACKING INTERACTIONS ; ALANINE MESOCRYSTALS ; FIBRIL FORMATION ; LONG-RANGE ; NANOSTRUCTURES ; NANOTUBES
WOS研究方向	Chemistry
语种	英语
出版者	NATURE PUBLISHING GROUP
WOS记录号	WOS:000489142200005
资助机构	National Natural Science Foundation of China ; National Natural Science Fund BRICS STI Framework Programme ; Innovation Research Community Science Fund ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (CAS) ; European Research Council under the European Union Horizon 2020 research and innovation programme (BISON)
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/31203]
专题	中国科学院过程工程研究所
通讯作者	Li, Junbai; Gazit, Ehud; Yan, Xuehai
作者单位	1.Chinese Acad Sci, Inst Proc Engn, Ctr Mesosci, Beijing, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing, Peoples R China 3.Tel Aviv Univ, George S Wise Fac Life Sci, Dept Mol Microbiol & Biotechnol, Tel Aviv, Israel 4.Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, BNLMS, Beijing, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Tel Aviv Univ, Iby & Aladar Fleischman Fac Engn, Dept Mat Sci & Engn, Tel Aviv, Israel
推荐引用方式 GB/T 7714	Yuan, Chengqian,Ji, Wei,Xing, Ruirui,et al. Hierarchically oriented organization in supramolecular peptide crystals[J]. NATURE REVIEWS CHEMISTRY,2019,3(10):567-588.
APA	Yuan, Chengqian,Ji, Wei,Xing, Ruirui,Li, Junbai,Gazit, Ehud,&Yan, Xuehai.(2019).Hierarchically oriented organization in supramolecular peptide crystals.NATURE REVIEWS CHEMISTRY,3(10),567-588.
MLA	Yuan, Chengqian,et al."Hierarchically oriented organization in supramolecular peptide crystals".NATURE REVIEWS CHEMISTRY 3.10(2019):567-588.