Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry

doi:10.1093/chromsci/bmw109

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	Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry
	Ling, Yun 1; Hu, Pei 1,2; Zhang, Lifang 1; Jin, Hongguang 1; Chen, Jian 1; Tao, Zhi 1; Huang, Ling 1; Ren, Ruoyu 1
刊名	JOURNAL OF CHROMATOGRAPHIC SCIENCE
	2016-10
卷号	54 期号:9 页码:1593-1604
ISSN号	0021-9665
DOI	10.1093/chromsci/bmw109
文献子类	Article
英文摘要	The dried fruit of Evodia rutaecarpa (Juss.) Benth. (ER) is a well-known traditional Chinese medicine and has been used in treatment of headache, abdominal pain, migraine, chill limbs, diarrhea, nausea, hyperbaropathy, dysmenorrheal and postpartum hemorrhage. In this work, a comprehensive characterization of chemical constituents in ER extract is carried out by high performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry. The increased power of higher mass resolution and exact mass measurements for precursor and fragment ions lead to detection of 3 acylgluconic acids, 3 flavonol glycosides, 6 limonoids and 24 alkaloids in ER, of which 6 quinolone alkaloids has not been reported previously to our best knowledge. This research enriches our knowledge of chemical constituents of ER and provides a reliable guide for further pharmacology and active mechanism study on this herb.
资助项目	Educational Department of Jiangxi Province of China[GJJ151075] ; Natural Science Foundation of Jiangxi Province of China[20161BAB215194] ; Jiujiang University[8500259]
WOS关键词	QUINOLONE ALKALOIDS
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	OXFORD UNIV PRESS INC
WOS记录号	WOS:000389139300018
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/275871]
专题	上海中药现代化研究中心
通讯作者	Ling, Yun
作者单位	1.Jiujiang Univ, Dept Pharmaceut & Life Sci, Jiujiang 332005, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Ling, Yun,Hu, Pei,Zhang, Lifang,et al. Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry[J]. JOURNAL OF CHROMATOGRAPHIC SCIENCE,2016,54(9):1593-1604.
APA	Ling, Yun.,Hu, Pei.,Zhang, Lifang.,Jin, Hongguang.,Chen, Jian.,...&Ren, Ruoyu.(2016).Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry.JOURNAL OF CHROMATOGRAPHIC SCIENCE,54(9),1593-1604.
MLA	Ling, Yun,et al."Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry".JOURNAL OF CHROMATOGRAPHIC SCIENCE 54.9(2016):1593-1604.