Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source

doi:10.1021/acs.orglett.7b01882

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	Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source
	Sun, Guanglong 2,3; Lv, Xue 2,3; Zhang, Yinan 1; Lei, Min2,3 ; Hu, Lihong 1
刊名	ORGANIC LETTERS
	2017-08-18
卷号	19 期号:16 页码:4235-4238
ISSN号	1523-7060
DOI	10.1021/acs.orglett.7b01882
文献子类	Article
英文摘要	A facile and practical method for the synthesis of aromatic aldehydes by palladium-catalyied reductive carbonylation starting from aryl iodides and HCOOH is described. Compared to the known formylation procedure, HCOOH serves not only as the most Convenient and environmental friendly Cl source but also as the reviving agent in the reductive elimination process of Pd-catalyst. Furthermore, this procedure is also apPlied successfully to modifitation of natural prochicts, such as vindoline, tabersonin, and viricamine, to obtain the corresponding products in good yields.
资助项目	National Natural Science Foundation of China[81473110] ; National Natural Science Foundation of China[81561148011] ; Special Fund for Strategic Pilot Technology Chinese Academy of Sciences[XDA12040303] ; Science Foundation of Shanghai[15431901100] ; Priority Academic Program Development of Jiangsu Higher Education Institutions[00000000]
WOS关键词	REDUCTIVE CARBONYLATION ; VINYLIC HALIDES ; FORMIC-ACID ; REGIOSELECTIVE HYDROFORMYLATION ; COUPLING REACTIONS ; N-FORMYLSACCHARIN ; AROMATIC IODIDES ; INDOLE ALKALOIDS ; H ARYLATION ; ALDEHYDES
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000408285600021
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272525]
专题	上海中药现代化研究中心
通讯作者	Lei, Min; Hu, Lihong
作者单位	1.Nanjing Univ Chinese Med, Stake Key Lab Cultivat Base TCM Qual & Efficacy, Jiangsu Collaborat Innovat Ctr Chinese Med Resour, Jiangsu Key Lab Funct Subst Chinese Med,Sch Pharm, Nanjing, Jiangsu, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Sun, Guanglong,Lv, Xue,Zhang, Yinan,et al. Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source[J]. ORGANIC LETTERS,2017,19(16):4235-4238.
APA	Sun, Guanglong,Lv, Xue,Zhang, Yinan,Lei, Min,&Hu, Lihong.(2017).Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source.ORGANIC LETTERS,19(16),4235-4238.
MLA	Sun, Guanglong,et al."Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source".ORGANIC LETTERS 19.16(2017):4235-4238.