Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility

doi:10.1002/adfm.201203738

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	Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility
	Yu, Hai-Jun1,4 ; Wang, Jun-Qiang 1; Shi, Xue-Tao 1; Louzguine-Luzgin, Dmitri V.1; Wu, Hong-Kai 1,3; Perepezko, John H.1,2
刊名	ADVANCED FUNCTIONAL MATERIALS
	2013-10-11
卷号	23 期号:38 页码:4793-4800
关键词	metallic glasses biomedical x nanostructures
ISSN号	1616-301X
DOI	10.1002/adfm.201203738
文献子类	Article
英文摘要	Magnesium-based metallic glasses (MMGs) show intriguing potentials for application as implantable biomaterials owing to their disordered atomic structure, good biodegradability, low elastic modulus, high strength, and large elasticity. However, despite of all these advantages, their brittleness is their Achilles' heel, which severely limits their application as biomedical materials. In the current study, a significantly improved ductility of MMGs under bending and tensile loading through minor alloying with rare-earth element ytterbium (Yb) at an atomic concentration of 2 and 4% is reported. The enhanced ductility is attributed to the increased density of shear bands close to fracture end and larger plastic zones on the fracture surface. In comparison with that of Yb-free control, in vitro cell culture study confirms an improved biocompatibility of MMGs alloyed with Yb as determined by MTT, live-dead, and cytoskeleton staining assays, respectively.
资助项目	Fusion Research Fund[00000000] ; World Premier International Research Center Initiative-Advanced Institute of Materials Research (WPI-AIMR), MEXT, Japan[00000000]
WOS关键词	IN-VITRO CORROSION ; MAGNESIUM ALLOY ; CA ALLOYS ; PART I ; DEFORMATION ; TEMPERATURE ; IMPLANTS ; BEHAVIOR ; CALCIUM ; BONE
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000327479200004
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/277422]
专题	药物制剂研究中心
通讯作者	Wang, Jun-Qiang
作者单位	1.Tohoku Univ, WPI Adv Inst Mat Res, Sendai, Miyagi 9808577, Japan; 2.Univ Wisconsin, Dept Mat Sci & Engn, Madison, WI 53706 USA 3.Hong Kong Univ Sci & Technol, Dept Chem, Hong Kong, Hong Kong, Peoples R China; 4.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, Shanghai 201203, Peoples R China;
推荐引用方式 GB/T 7714	Yu, Hai-Jun,Wang, Jun-Qiang,Shi, Xue-Tao,et al. Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility[J]. ADVANCED FUNCTIONAL MATERIALS,2013,23(38):4793-4800.
APA	Yu, Hai-Jun,Wang, Jun-Qiang,Shi, Xue-Tao,Louzguine-Luzgin, Dmitri V.,Wu, Hong-Kai,&Perepezko, John H..(2013).Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility.ADVANCED FUNCTIONAL MATERIALS,23(38),4793-4800.
MLA	Yu, Hai-Jun,et al."Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility".ADVANCED FUNCTIONAL MATERIALS 23.38(2013):4793-4800.