Two-way effects of surfactants on Pickering emulsions stabilized by the self-assembled microcrystals of alpha-cyclodextrin and oil

doi:10.1039/c4cp00807c

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	Two-way effects of surfactants on Pickering emulsions stabilized by the self-assembled microcrystals of alpha-cyclodextrin and oil
	Li, Xue 1,2; Li, Haiyan1 ; Xiao, Qun 3; Wang, Liuyi 3; Wang, Manli 1; Lu, Xiaolong 1; York, Peter 4; Shi, Senlin 2; Zhang, Jiwen1
刊名	PHYSICAL CHEMISTRY CHEMICAL PHYSICS
	2014
卷号	16 期号:27 页码:14059-14069
ISSN号	1463-9076
DOI	10.1039/c4cp00807c
文献子类	Article
英文摘要	The influence of surfactants on the stability of cyclodextrin (CD) Pickering emulsions is not well understood. In this study, we report two-way effects of Tween 80 and soybean lecithin (PL) on the long term stability of Pickering emulsions stabilized by the self-assembled microcrystals of alpha-CD and medium chain triglycerides (MCT). The CD emulsions in the absence and presence of Tween 80 or PL at different concentrations were prepared and characterized by the droplet size, viscosity, contact angle, interfacial tension and residual emulsion values. After adding Tween 80 and PL, similar effects on the size distribution and contact angle were observed. However, changes of viscosity and interfacial tension were significantly different and two-way effects on the stability were found: (i) synergistic enhancement by Tween 80; (ii) inhibition at low and enhancement at high concentrations by PL. The stability enhancement of Tween 80 was due to the interfacial tension decrease caused by the interaction of Tween 80 with CD at the o/w interface at lower concentrations, and significant viscosity increase caused by the Tween 80-CD assembly in the continuous phase. For PL at low concentrations, the replacement of alpha-CD/MCT by alpha-CD/PL particles at the o/w interface was observed, leading to inhibitory effects. High concentrations of PL resulted in an extremely low interfacial tension and stable emulsion. In conclusion, the extensive inclusion of surfactants by CD leads to their unique effects on the stability of CD emulsions, for which the changes of viscosity and interfacial tension caused by host-guest interactions play important roles.
资助项目	National Natural Science Foundation of China[81373358] ; Chinese Academy of Sciences[00000000]
WOS关键词	IN-WATER EMULSIONS ; SILICA NANOPARTICLES ; BETA-CYCLODEXTRIN ; FE3O4 NANOPARTICLES ; INCLUSION COMPLEXES ; OLEIC-ACID ; PARTICLES ; TRIGLYCERIDE ; EMULSIFIER ; INTERFACES
WOS研究方向	Chemistry ; Physics
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000338116700056
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/277281]
专题	药物制剂研究中心
通讯作者	Shi, Senlin
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Drug Delivery Syst, Shanghai 201203, Peoples R China; 2.Zhejiang Chinese Med Univ, Sch Pharm, Hangzhou 310000, Zhejiang, Peoples R China; 3.Hainan Weikang Pharmaceut Co Ltd, Anqing 246000, Peoples R China; 4.Univ Bradford, Bradford BD7 1DP, W Yorkshire, England
推荐引用方式 GB/T 7714	Li, Xue,Li, Haiyan,Xiao, Qun,et al. Two-way effects of surfactants on Pickering emulsions stabilized by the self-assembled microcrystals of alpha-cyclodextrin and oil[J]. PHYSICAL CHEMISTRY CHEMICAL PHYSICS,2014,16(27):14059-14069.
APA	Li, Xue.,Li, Haiyan.,Xiao, Qun.,Wang, Liuyi.,Wang, Manli.,...&Zhang, Jiwen.(2014).Two-way effects of surfactants on Pickering emulsions stabilized by the self-assembled microcrystals of alpha-cyclodextrin and oil.PHYSICAL CHEMISTRY CHEMICAL PHYSICS,16(27),14059-14069.
MLA	Li, Xue,et al."Two-way effects of surfactants on Pickering emulsions stabilized by the self-assembled microcrystals of alpha-cyclodextrin and oil".PHYSICAL CHEMISTRY CHEMICAL PHYSICS 16.27(2014):14059-14069.