Inducing effect of resveratrol on anoikis of gastric cancer cells

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 药理学第一研究室

	Inducing effect of resveratrol on anoikis of gastric cancer cells
	Li Ying 1; Yao Libo 1; Wang Lifeng 1; Han Jiong 1; Han Yueheng 1; Liu Xinping 1; Lin Shuxin 2; Yu Qiang3
刊名	Chinese Traditional and Herbal Drugs
	2004
卷号	35 期号:10 页码:1138-1140
关键词	resveratrol anoikis gastric cancer cells
ISSN号	0253-2670
其他题名	白藜芦醇诱导胃癌细胞脱落凋亡
文献子类	Article
英文摘要	Object To study the inducing of resveratrol on anoikis of gastric cancer cells. Methods Cell morphology observation, Annxin-V and PI staining, and Flow cytometry (FCM) assay were used to observe the inducing effect of resveratrol (0. 1, 0. 2, 0. 5 mmol/L) on cell growth, cell cycles and anoikis of the gastric cancer cells (BGC823, SGC7901, and HGC27) cultured in suspension. Results Cluster growth of gastric cancer cells cultured in suspension was observed by invert microscope. Resveratrol (0. 1 mmol/L) could inhibit the gastric cancer cells resistant to anoikis to form cluster by FCM assay and Annx-in-V and PI staining. Resveratrol (0. 5 mmol/L) could arrest the suspended gastric cancer cells (BGC823, SGC7901, and HGC27) to G_o/G_1, S, G_2/M phase respectively and induce the gastric cancer cells to anoikis, and the anoikis rate of HGC27 was around 19. 3%, which was higher than that of other two cells. Conclusion Resveratrol can induce gastric cancer cells to anoikis.
资助项目	国家自然科学基金[00000000] ; 军队"十五"科研基金重点课题[00000000]
WOS研究方向	General & Internal Medicine (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:1654282
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/268387]
专题	药理学第一研究室
通讯作者	Yu Qiang
作者单位	1.Department of Biochemistry and Molecular Biology, Xian, Shanxi 710032, China.; 2.Department of Pathophysiology, Fourth Military Medical Univer-sity, Xian, Shanxi 710032, China.; 3.Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
推荐引用方式 GB/T 7714	Li Ying,Yao Libo,Wang Lifeng,et al. Inducing effect of resveratrol on anoikis of gastric cancer cells[J]. Chinese Traditional and Herbal Drugs,2004,35(10):1138-1140.
APA	Li Ying.,Yao Libo.,Wang Lifeng.,Han Jiong.,Han Yueheng.,...&Yu Qiang.(2004).Inducing effect of resveratrol on anoikis of gastric cancer cells.Chinese Traditional and Herbal Drugs,35(10),1138-1140.
MLA	Li Ying,et al."Inducing effect of resveratrol on anoikis of gastric cancer cells".Chinese Traditional and Herbal Drugs 35.10(2004):1138-1140.