Biscinchona alkaloids as highly efficient bifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroalkenes at ambient temperature

doi:10.1016/j.tet.2011.08.070

	Biscinchona alkaloids as highly efficient bifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroalkenes at ambient temperature
	Li, Fei 1; Li, Ying-Zi 1; Jia, Zhen-Shan 1; Xu, Ming-Hua2 ; Tian, Ping 1; Lin, Guo-Qiang 1
刊名	TETRAHEDRON
	2011-12-30
卷号	67 期号:52 页码:10186-10194
关键词	Bifinctional Biscinchona alkaloids Nitroalkenes Conjugate addition Baclofen
ISSN号	0040-4020
DOI	10.1016/j.tet.2011.08.070
文献子类	Article
英文摘要	The novel bifunctional bisalkaloids have been developed as highly efficient catalysts for the asymmetric conjugate addition of 1,3-dicarbonyl compounds to nitroalkenes with low catalyst loading (1 mol %) at ambient temperature, providing the products with excellent enantioselectivities (up to 97% ee). Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.
资助项目	Major State Basic Research Development Program[2010CB833302] ; Shanghai Municipal Committee of Science and Technology[09JC1417300]
WOS关键词	BAYLIS-HILLMAN REACTION ; ENANTIOSELECTIVE MICHAEL ADDITION ; 1,3-DICARBONYL COMPOUNDS ; CINCHONA ALKALOIDS ; QUATERNARY STEREOCENTERS ; TERTIARY STEREOCENTERS ; ADJACENT QUATERNARY ; ORGANIC CATALYST ; HENRY REACTION ; CHIRAL AMINES
WOS研究方向	Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000298274600014
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/278297]
专题	药物化学研究室
通讯作者	Tian, Ping
作者单位	1.Chinese Acad Sci, Shanghai Inst Organ Chem, CAS Key Lab Synthet Chem Nat Subst, Shanghai 200032, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Li, Fei,Li, Ying-Zi,Jia, Zhen-Shan,et al. Biscinchona alkaloids as highly efficient bifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroalkenes at ambient temperature[J]. TETRAHEDRON,2011,67(52):10186-10194.
APA	Li, Fei,Li, Ying-Zi,Jia, Zhen-Shan,Xu, Ming-Hua,Tian, Ping,&Lin, Guo-Qiang.(2011).Biscinchona alkaloids as highly efficient bifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroalkenes at ambient temperature.TETRAHEDRON,67(52),10186-10194.
MLA	Li, Fei,et al."Biscinchona alkaloids as highly efficient bifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroalkenes at ambient temperature".TETRAHEDRON 67.52(2011):10186-10194.