Improved laboratory synthesis of YC-071, a potent azole antifungal agent

doi:10.3184/174751917X14902201357419

	Improved laboratory synthesis of YC-071, a potent azole antifungal agent
	Zheng, Yazhou 3; Qian, Anran 1,2; Ling, Chenyu 1,2; Cao, Xufeng 1,2; Cui, YongMei 3; Yang, Yushe1,2
刊名	JOURNAL OF CHEMICAL RESEARCH
	2017-04
期号	4 页码:241-245
关键词	triazole reductive amination intramolecular cyclisation antifungal agent
ISSN号	1747-5198
DOI	10.3184/174751917X14902201357419
文献子类	Article
英文摘要	An improved laboratory synthesis of YC-071, a potent azole antifungal agent, has been developed. Compared with the original route, the new route is operationally simple, requiring only limited purification of all the intermediates. The new route is an important scalable synthesis, which meets the need for YC-071 for use in preclinical studies.
资助项目	National Natural Science Foundation of China[21402223]
WOS关键词	DERIVATIVES ; DISCOVERY ; DESIGN
WOS研究方向	Chemistry
语种	英语
出版者	SCIENCE REVIEWS 2000 LTD
WOS记录号	WOS:000416040700013
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272708]
专题	药物化学研究室
通讯作者	Yang, Yushe
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Shanghai Univ, Coll Sci, Dept Chem, Shanghai 200444, Peoples R China;
推荐引用方式 GB/T 7714	Zheng, Yazhou,Qian, Anran,Ling, Chenyu,et al. Improved laboratory synthesis of YC-071, a potent azole antifungal agent[J]. JOURNAL OF CHEMICAL RESEARCH,2017(4):241-245.
APA	Zheng, Yazhou,Qian, Anran,Ling, Chenyu,Cao, Xufeng,Cui, YongMei,&Yang, Yushe.(2017).Improved laboratory synthesis of YC-071, a potent azole antifungal agent.JOURNAL OF CHEMICAL RESEARCH(4),241-245.
MLA	Zheng, Yazhou,et al."Improved laboratory synthesis of YC-071, a potent azole antifungal agent".JOURNAL OF CHEMICAL RESEARCH .4(2017):241-245.