Studies on chemical constituents of Sarcophyton trocheliophrum

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	Studies on chemical constituents of Sarcophyton trocheliophrum
	He Lingli 1; Liu Haili 2; Liang Linfu 2; Zhang Hongbin 1; Guo Yuewei2
刊名	Chinese Journal of Marine Drugs
	2013
卷号	32 期号:2 页码:37-40
关键词	Sarcophyton trocheliophrum chemical constituents cembrane diterpenes
ISSN号	1002-3461
其他题名	中国南海圆盘肉芝软珊瑚的化学成分研究
文献子类	Article
英文摘要	Objective To investigate the chemical constituents of the soft coral Sarcophyton trocheliophrum. Methods The chemical constituents were isolated and purified using column chromatography. Their structures were determined through the analysis of spectroscopic data.Results Five known cembrane diterpenes were identified as 7R~,8R~-epoxy-isoneocembrane A-16-oic methyl ester(1),4-epithunbergol(2),(-)-sarcophytoxide(3),ent-sarcophine(4),and 2-hydroperoxysarcophine(5),respectively. Conclusion Compounds 1,2,and 5 were obtained from this genus for the first time.Compound 2 exhibited weak cytotoxicity against A-549human lung carcinoma and HL-60human promyelocytic leukemia cell lines,while compound 4 showed weak inhibitory activity against acetylcholinesterase.
资助项目	国家海洋863计划[00000000] ; 国家自然科学基金[00000000] ; 中国科学院国家新药研究重点实验室项目[00000000] ; 欧盟第七框架计划-IRS-ES项目[00000000]
WOS研究方向	Pharmacology & Pharmacy (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:4814095
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/267785]
专题	天然药物化学研究室
作者单位	1.Department of Pharmaceutical Engineering,HeFei University of Technology, Hefei, Anhui 230009, China.; 2.State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Science, Hefei, Anhui 230009, China.
推荐引用方式 GB/T 7714	He Lingli,Liu Haili,Liang Linfu,et al. Studies on chemical constituents of Sarcophyton trocheliophrum[J]. Chinese Journal of Marine Drugs,2013,32(2):37-40.
APA	He Lingli,Liu Haili,Liang Linfu,Zhang Hongbin,&Guo Yuewei.(2013).Studies on chemical constituents of Sarcophyton trocheliophrum.Chinese Journal of Marine Drugs,32(2),37-40.
MLA	He Lingli,et al."Studies on chemical constituents of Sarcophyton trocheliophrum".Chinese Journal of Marine Drugs 32.2(2013):37-40.