Dysohonin A, a meroditerpenoid incorporating a 6,15,6-fused heterotricyclic ring system from Dysoxylum hongkongense | |
Zhao, Jin-Xin; Liu, Cui-Ping; Zhang, Meng-Meng; Li, Jia; Yue, Jian-Min | |
刊名 | ORGANIC CHEMISTRY FRONTIERS |
2018-07-21 | |
卷号 | 5期号:14页码:2202-2207 |
ISSN号 | 2052-4129 |
DOI | 10.1039/c8qo00469b |
文献子类 | Article |
英文摘要 | Dysohonin A (1), a meroditerpenoid incorporating an unprecedented 6,15,6-fused heterotricyclic ring system, along with three new biogenetically related meroditerpenoids dysohonins B-D (2-4) were isolated from Dysoxylum hongkongense. Their structures with absolute configurations were well established by a combined method. The plausible biosynthetic pathways of 1-4 were proposed. All the compounds exhibited PTP1B inhibitory activities. |
资助项目 | National Natural Science Foundation of the People's Republic of China[21532007] |
WOS关键词 | ABSOLUTE-CONFIGURATION ; CIRCULAR-DICHROISM ; STERIC BULK ; A-D ; DEPROTONATION ; MO-2(OAC)(4) ; COMPLEXES ; 1,2-DIOLS ; STEROIDS |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000438245300009 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/279656] |
专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Yue, Jian-Min |
作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Zhao, Jin-Xin,Liu, Cui-Ping,Zhang, Meng-Meng,et al. Dysohonin A, a meroditerpenoid incorporating a 6,15,6-fused heterotricyclic ring system from Dysoxylum hongkongense[J]. ORGANIC CHEMISTRY FRONTIERS,2018,5(14):2202-2207. |
APA | Zhao, Jin-Xin,Liu, Cui-Ping,Zhang, Meng-Meng,Li, Jia,&Yue, Jian-Min.(2018).Dysohonin A, a meroditerpenoid incorporating a 6,15,6-fused heterotricyclic ring system from Dysoxylum hongkongense.ORGANIC CHEMISTRY FRONTIERS,5(14),2202-2207. |
MLA | Zhao, Jin-Xin,et al."Dysohonin A, a meroditerpenoid incorporating a 6,15,6-fused heterotricyclic ring system from Dysoxylum hongkongense".ORGANIC CHEMISTRY FRONTIERS 5.14(2018):2202-2207. |
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