Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes

doi:10.1007/s00726-012-1404-x

	Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes
	Ding, Xiao 3; Wang, Hengshuai 3; Wang, Jiang3 ; Wang, Sinan 3; Lin, Daizong 3; Lv, Li 3; Zhou, Yu3 ; Luo, Xiaomin3 ; Jiang, Hualiang3 ; Luis Acena, Jose 2
刊名	AMINO ACIDS
	2013-02
卷号	44 期号:2 页码:791-796
关键词	Diels-Alder reaction Nickel (II) beta-Alanine beta-Aminocyclohexane carboxylic acids
ISSN号	0939-4451
DOI	10.1007/s00726-012-1404-x
文献子类	Article
英文摘要	This paper describes the design and synthesis of a new class of beta-alanine derived dienes stabilized by Ni(II)-complex. Preliminary study of their Diels-Alder cycloaddition reactions with several types of dienophiles demonstrates their significant synthetic potential for the preparation of various polyfunctional beta-aminocyclohexane carboxylic acids.
资助项目	National Basic Research Program of China[2009CB940903] ; National Basic Research Program of China[2009CB918502] ; National Natural Science Foundation of China[20721003] ; National Natural Science Foundation of China[81025017] ; National S&T Major Projects[2012ZX09103-101-072] ; China-EU Science and Technology Cooperation Project[1109] ; Silver Project[260644]
WOS关键词	MICHAEL ADDITION-REACTIONS ; NUCLEOPHILIC GLYCINE EQUIVALENTS ; EFFICIENT ASYMMETRIC-SYNTHESIS ; SUBSTITUTED PYROGLUTAMIC ACIDS ; VIRTUALLY COMPLETE CONTROL ; CHIRAL NI(II) COMPLEX ; LARGE-SCALE SYNTHESIS ; ALPHA-AMINO ; ALDOL REACTIONS ; FACE DIASTEREOSELECTIVITY
WOS研究方向	Biochemistry & Molecular Biology
语种	英语
出版者	SPRINGER WIEN
WOS记录号	WOS:000313794600046
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/277747]
专题	药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室药物发现与设计中心
通讯作者	Liu, Hong
作者单位	1.Univ Basque Country UPV EHU, San Sebastian, Spain 2.Basque Fdn Sci, IKERBASQUE, Bilbao 48011, Spain; 3.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China;
推荐引用方式 GB/T 7714	Ding, Xiao,Wang, Hengshuai,Wang, Jiang,et al. Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes[J]. AMINO ACIDS,2013,44(2):791-796.
APA	Ding, Xiao.,Wang, Hengshuai.,Wang, Jiang.,Wang, Sinan.,Lin, Daizong.,...&Liu, Hong.(2013).Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes.AMINO ACIDS,44(2),791-796.
MLA	Ding, Xiao,et al."Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes".AMINO ACIDS 44.2(2013):791-796.