Eurifoloids A-R, Structurally Diverse Diterpenoids from Euphorbia neriifolia

doi:10.1021/np5004752

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	Eurifoloids A-R, Structurally Diverse Diterpenoids from Euphorbia neriifolia
	Zhao, Jin-Xin 1; Liu, Cui-Ping 1; Qi, Wei-Yan 1; Han, Mei-Ling 1; Han, Ying-Shan 2; Wainberg, Mark A.2; Yue, Jian-Min1
刊名	JOURNAL OF NATURAL PRODUCTS
	2014-10
卷号	77 期号:10 页码:2224-2233
ISSN号	0163-3864
DOI	10.1021/np5004752
文献子类	Article
英文摘要	Eighteen new diterpenoids, named eurifoloids A-R (1-18), including ingenane (1 and 2), abietane (3-7), isopimarane (8-12), and ent-atisane (13-18) types, along with four known analogues were isolated from Euphorbia neriifolia. Eurifoloid M (13) represents a rare class of ent-atisane-type norditerpenoid. Eurifoloids E (5) and F (6) exhibited significant anti-HIV activities, with EC50 values of 3.58 +/- 0.31 (SI = 8.6) and 7.40 +/- 0.94 mu M (SI = 10.3), respectively.
资助项目	National Natural Science Foundation[U1302222] ; National Natural Science Foundation[81273398] ; Foundation from the Ministry of Science and Technology of P. R. China[2012CB721105]
WOS关键词	LATEX ; CONSTITUENTS ; TRITERPENES ; TERPENOIDS
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000343786100009
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/276879]
专题	天然药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Yue, Jian-Min
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200031, Peoples R China; 2.McGill Univ, Jewish Gen Hosp, AIDS Ctr, Lady Davis Inst Med Res, Montreal, PQ H3T 1E2, Canada
推荐引用方式 GB/T 7714	Zhao, Jin-Xin,Liu, Cui-Ping,Qi, Wei-Yan,et al. Eurifoloids A-R, Structurally Diverse Diterpenoids from Euphorbia neriifolia[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(10):2224-2233.
APA	Zhao, Jin-Xin.,Liu, Cui-Ping.,Qi, Wei-Yan.,Han, Mei-Ling.,Han, Ying-Shan.,...&Yue, Jian-Min.(2014).Eurifoloids A-R, Structurally Diverse Diterpenoids from Euphorbia neriifolia.JOURNAL OF NATURAL PRODUCTS,77(10),2224-2233.
MLA	Zhao, Jin-Xin,et al."Eurifoloids A-R, Structurally Diverse Diterpenoids from Euphorbia neriifolia".JOURNAL OF NATURAL PRODUCTS 77.10(2014):2224-2233.