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	Flueggether A and Virosinine A, Anti-HIV Alkaloids from Flueggea virosa
	Zhang, Hua1; Zhu, Kong-Kai1; Han, Ying-Shan2; Luo, Cheng1; Wainberg, Mark A.2; Yue, Jian-Min1
刊名	ORGANIC LETTERS
	2015-12-18
卷号	17期号:24页码:6274-6277
ISSN号	1523-7060
DOI	10.1021/acs.orglett.5b03320
文献子类	Article
英文摘要	Two new alkaloids flueggether A (1) and virosinine A (2), Were isolated from Chinese Medicinal plant, Flueggea virosa. Their Structures were assigned via spectroscopic methods with the absolute configurations of 1 and 2 Being established by X-ray diffraction analysis and calculated electronic circular dichroism data, respectively. Compound 1 represents the first example with an ether bridge of Securinega alkaloid oligomers, and 2 bears a new heterocyclic backbone. Both alkaloids showed mild in vitro anti-HIV activity.
资助项目	National Natural Science Foundation[81322045] ; National Natural Science Foundation[81321092]
WOS关键词	DIMERIC INDOLIZIDINE ALKALOIDS ; SECURINEGA ALKALOIDS ; ROOTS
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000366878300085
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/276282]
专题	天然药物化学研究室 中科院受体结构与功能重点实验室 期刊编辑部 新药研究国家重点实验室 分析化学研究室
通讯作者	Yue, Jian-Min
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 2.McGill Univ, Jewish Gen Hosp, Lady Davis Inst Med Res, Aids Ctr, Montreal, PQ H3T 1E2, Canada
推荐引用方式 GB/T 7714	Zhang, Hua,Zhu, Kong-Kai,Han, Ying-Shan,et al. Flueggether A and Virosinine A, Anti-HIV Alkaloids from Flueggea virosa[J]. ORGANIC LETTERS,2015,17(24):6274-6277.
APA	Zhang, Hua,Zhu, Kong-Kai,Han, Ying-Shan,Luo, Cheng,Wainberg, Mark A.,&Yue, Jian-Min.(2015).Flueggether A and Virosinine A, Anti-HIV Alkaloids from Flueggea virosa.ORGANIC LETTERS,17(24),6274-6277.
MLA	Zhang, Hua,et al."Flueggether A and Virosinine A, Anti-HIV Alkaloids from Flueggea virosa".ORGANIC LETTERS 17.24(2015):6274-6277.

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