Fluorescent glycoprobes: a sweet addition for improved sensing

doi:10.1039/c6cc06875h

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	Fluorescent glycoprobes: a sweet addition for improved sensing
	He, Xiao-Peng 1,2; Zang, Yi3 ; James, Tony D.4; Li, Jia3 ; Chen, Guo-Rong 1,2; Xie, Juan 5
刊名	CHEMICAL COMMUNICATIONS
	2017-01-04
卷号	53 期号:1 页码:82-90
ISSN号	1359-7345
DOI	10.1039/c6cc06875h
文献子类	Article
英文摘要	The development of small-molecule fluorescent probes for the detection of ions and biomacromolecules and for cellular and in vivo imaging has been a very active research area. Nevertheless, many problems exist for traditional probes including their poor water solubility, toxicity and the inability to target specific tissues. Because of the enhanced water solubility, biocompatibility and targeting ability for specific cells, there has been an emerging movement to use carbohydrates as either the backbone or as a warhead to decorate conventional fluorescent probes, producing "glycoprobes'' with enhanced properties. This feature article provides an overview of recently developed glycoprobes for ion and protein detection as well as targeted (receptor targeting) cellular imaging and theranostics. Here, we summarise the tactics for preparing small molecular glycoprobes and their supramolecular 2D material composites.
资助项目	973 project[2013CB733700] ; Science and Technology Commission of Shanghai Municipality[15540723800] ; National Natural Science Foundation of China[21572058] ; National Natural Science Foundation of China[21576088] ; Shanghai Rising-Star Program[16QA1401400]
WOS关键词	AGGREGATION-INDUCED-EMISSION ; CUAAC CLICK CHEMISTRY ; GRAPHENE OXIDE ; ASIALOGLYCOPROTEIN RECEPTOR ; SELECTIVE DETECTION ; HYDROGEN-SULFIDE ; AQUEOUS-MEDIA ; HINGE SUGAR ; METAL-IONS ; HG2+ ION
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000391607100005
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/275686]
专题	国家新药筛选中心中科院受体结构与功能重点实验室新药研究国家重点实验室药物安全性评价中心
通讯作者	James, Tony D.; Li, Jia; Chen, Guo-Rong; Xie, Juan
作者单位	1.East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China; 2.East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, State Key Lab Drug Res, 189 Guo Shoujing Rd, Shanghai 201203, Peoples R China; 4.Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England; 5.Univ Paris Saclay, CNRS UMR 8531, PPSM, ENS Cachan, 61 Av President Wilson, F-94230 Cachan, France
推荐引用方式 GB/T 7714	He, Xiao-Peng,Zang, Yi,James, Tony D.,et al. Fluorescent glycoprobes: a sweet addition for improved sensing[J]. CHEMICAL COMMUNICATIONS,2017,53(1):82-90.
APA	He, Xiao-Peng,Zang, Yi,James, Tony D.,Li, Jia,Chen, Guo-Rong,&Xie, Juan.(2017).Fluorescent glycoprobes: a sweet addition for improved sensing.CHEMICAL COMMUNICATIONS,53(1),82-90.
MLA	He, Xiao-Peng,et al."Fluorescent glycoprobes: a sweet addition for improved sensing".CHEMICAL COMMUNICATIONS 53.1(2017):82-90.