Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes

doi:10.1007/s10886-007-9387-x

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	Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes
	Manzo, Emiliano ; Gavagnin, Margherita ; Somerville, Michael J.; Mao, Shui-Chun ; Ciavatta, M. Letizia ; Mollo, Ernesto ; Schupp, Peter J.; Garson, Mary J.; Guo, Yue-Wei; Cimino, Guido
刊名	JOURNAL OF CHEMICAL ECOLOGY
	2007-12
卷号	33 期号:12 页码:2325-2336
关键词	Opisthobranchia Chromodorididae Glossodoris sesterterpenoids scalaranes
ISSN号	0098-0331
DOI	10.1007/s10886-007-9387-x
文献子类	Article
英文摘要	With the aim of establishing whether the oxidation of the tricyclic carbon skeleton of scalaradial (1) is specific to Glossodoris mollusks, the chemical investigation of specimens of Glossodoris pallida from two distinct geographical areas (China and Guam) and of Glossodoris vespa and Glossodoris averni from Eastern Australia was performed. 12-Deacetoxy-12-oxo-scalaradial (4), recently reported from another Glossodoris nudibranch, was the main metabolite of G. pallida from China, G. vespa, and G. averni. A series of scalarane compounds 3 and 5-11, including the unprecedented 12,16-deacetoxy-12-oxo-scalarafuran 5, was isolated from the mollusks. Interestingly, a population of G. pallida from Guam displayed a different scalarane pattern that was characterized by scalaradial (1), deacetyl scalaradial (2), and deoxoscalarin (3), thus confirming previous reports. The specific occurrence of 12-keto-derivatives in some nudibranchs of the genus Glossodoris is discussed.
资助项目	NIGMS NIH HHS[SO6-GM-4479615] ; NIGMS NIH HHS[SO6-GM-44796-16A]
WOS关键词	CYTOTOXIC SESTERTERPENOIDS ; CHROMODORIS-INORNATA ; SPONGIA-OFFICINALIS ; ATROMARGINATA ; METABOLITES ; ECOLOGY
WOS研究方向	Biochemistry & Molecular Biology ; Environmental Sciences & Ecology
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000251425900013
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/273106]
专题	新药研究国家重点实验室中科院受体结构与功能重点实验室
通讯作者	Gavagnin, Margherita
作者单位	1.Univ Guam, Marine Lab, UOG Stn, Mangilao, GU 96923 USA 2.CNR, Inst Chim Biomol, I-80078 Pozzuoli, Italy 3.Univ Queensland, Sch Mol & Microbiol Sci, Brisbane, Qld 4072, Australia 4.Chinese Acad Sci, Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Manzo, Emiliano,Gavagnin, Margherita,Somerville, Michael J.,et al. Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes[J]. JOURNAL OF CHEMICAL ECOLOGY,2007,33(12):2325-2336.
APA	Manzo, Emiliano.,Gavagnin, Margherita.,Somerville, Michael J..,Mao, Shui-Chun.,Ciavatta, M. Letizia.,...&Cimino, Guido.(2007).Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes.JOURNAL OF CHEMICAL ECOLOGY,33(12),2325-2336.
MLA	Manzo, Emiliano,et al."Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes".JOURNAL OF CHEMICAL ECOLOGY 33.12(2007):2325-2336.