Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia

doi:10.1016/j.tet.2008.03.016

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	Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia
	Ciavatta, Maria Letizia 1; Pilar Lopez-Gresa, M.2; Gavagnin, Margherita 1; Nicoletti, Rosario 3; Manzo, Emiliano 1; Mollo, Ernesto 1; Guo, Yue-Wei4 ; Cimino, Guido 1
刊名	TETRAHEDRON
	2008-05-26
卷号	64 期号:22 页码:5365-5369
关键词	hexahydrobenzopyrane derivatives cytosporins marine fungus Eutypella scoporia carbonate NMR Mosher method pulmonata
ISSN号	0040-4020
DOI	10.1016/j.tet.2008.03.016
文献子类	Article
英文摘要	Chemical investigation of the culture broth of the fungus Eutypella scoparia ICB-OBX, isolated from the marine pulmonate mollusc Onchidium sp., led to the finding of novel compounds 1 and 2, structurally related to angiotensin II binding inhibitors cytosporins, along with unrelated known nitrogen metabolites (compounds 3-5). The structure and the relative stereochemistry of the novel metabolites were assigned mainly by a detailed analysis of two-dimensional NMR techniques whereas the absolute stereochemistry was proposed by modified Mosher's method. Compound 2 contains an unusual cyclic carbonate functionality that is rare among natural products. (C) 2008 Elsevier Ltd. All rights reserved.
WOS关键词	LIPID DROPLET FORMATION ; ABSOLUTE-CONFIGURATIONS ; ENDOPHYTIC FUNGUS ; MOUSE MACROPHAGES ; MOSHER METHOD ; SEA HARE ; METABOLITES ; PHENOCHALASINS ; POLYKETIDES ; INHIBITORS
WOS研究方向	Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000256179700063
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272916]
专题	天然药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Ciavatta, Maria Letizia
作者单位	1.CNR, Ist Chim Biomol, I-80078 Pozzuoli, Italy; 2.Univ Politecn Valencia, Ctr Ecol Quim Agricola, Valencia 46022, Spain; 3.CRA, Ist Sperimentale Tabacco, I-84018 Scafati, Italy; 4.Chinese Acad Sci, Shanghai Inst Mat Med, Inst Biol Sci, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Ciavatta, Maria Letizia,Pilar Lopez-Gresa, M.,Gavagnin, Margherita,et al. Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia[J]. TETRAHEDRON,2008,64(22):5365-5369.
APA	Ciavatta, Maria Letizia.,Pilar Lopez-Gresa, M..,Gavagnin, Margherita.,Nicoletti, Rosario.,Manzo, Emiliano.,...&Cimino, Guido.(2008).Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia.TETRAHEDRON,64(22),5365-5369.
MLA	Ciavatta, Maria Letizia,et al."Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia".TETRAHEDRON 64.22(2008):5365-5369.