Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene

doi:10.1016/j.colsurfb.2018.10.050

	Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene
	Geng, Hao; Wang, Tianbo; Cao, Huiliang; Zhu, Hongqin; Di, Zengfeng; Liu, Xuanyong
刊名	COLLOIDS AND SURFACES B-BIOINTERFACES
	2019
卷号	173 页码:681
关键词	Fluorinated graphene Plasma modification Antibacterial property Biological response
ISSN号	0927-7765
DOI	10.1016/j.colsurfb.2018.10.050
文献子类	Article
英文摘要	Graphene halides are promising two-dimensional systems which have interesting physical and chemical properties. In particular, high quality fluorinated graphene offers a great potential in modulating variable properties by regulating its surface microstructure. Moreover, the fluorine introduction and carbon-fluorine bonding characters will enable some interesting biological response. Here, the biological responses to bacteria and cells of fluorinated graphene were studied. Present work revealed that partially fluorinated graphene behaved satisfactory antibacterial ability. Fluorinated graphene showed well facilitating function to cell adhesion in early period, however, after a longer incubation period, the enhanced intracellular ROS level in rBMSCs on the fully fluorinated graphene gives rise to the decrease of cell viability. It was found that there is no statistical difference in the activity of alkaline phosphatase (ALP) and matrix mineralization of rBMSCs on pristine graphene, partially fluorinated graphene and fluorographene. In addition, the introduction of fluorine into pristine graphene plane reduced the adhesion and aggregation of blood platelets due to the attenuation of pi-pi interaction between material surface and blood protein. The findings in this work revealed that partial fluorinated graphene exhibited better antibacterial ability and cytocompatibility, outperforming pristine graphene and fluorographene.
WOS研究方向	Biophysics ; Chemistry ; Materials Science
语种	英语
出版者	ELSEVIER SCIENCE BV
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/27436]
专题	中国科学院上海硅酸盐研究所
推荐引用方式 GB/T 7714	Geng, Hao,Wang, Tianbo,Cao, Huiliang,et al. Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2019,173:681.
APA	Geng, Hao,Wang, Tianbo,Cao, Huiliang,Zhu, Hongqin,Di, Zengfeng,&Liu, Xuanyong.(2019).Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene.COLLOIDS AND SURFACES B-BIOINTERFACES,173,681.
MLA	Geng, Hao,et al."Antibacterial ability, cytocompatibility and hemocompatibility of fluorinated graphene".COLLOIDS AND SURFACES B-BIOINTERFACES 173(2019):681.