Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reactions

doi:10.1002/anie.201805664

	Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reactions
	Tang, Zhongmin; Liu, Yanyan; He, Mingyuan; Bu, Wenbo
刊名	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
	2019-01-21
卷号	58 期号:4 页码:946
关键词	chemodynamic therapy external energy fields Fenton reaction nanomaterials selection reaction environment
ISSN号	1433-7851
DOI	10.1002/anie.201805664
文献子类	Review
英文摘要	Tailored to the specific tumour microenvironment, which involves acidity and the overproduction of hydrogen peroxide, advanced nanotechnology has been introduced to generate the hydroxyl radical ((OH)-O-.) primarily for tumour chemodynamic therapy (CDT) through the Fenton and Fenton-like reactions. Numerous studies have investigated the enhancement of CDT efficiency, primarily the increase in the amount of (OH)-O-. generated. Notably, various strategies based on the Fenton reaction have been employed to enhance (OH)-O-. generation, including nanomaterials selection, modulation of the reaction environment, and external energy fields stimulation, which are discussed systematically in this Minireview. Furthermore, the potential challenges and the methods used to facilitate CDT effectiveness are also presented to support this cutting-edge research area.
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/27390]
专题	中国科学院上海硅酸盐研究所
推荐引用方式 GB/T 7714	Tang, Zhongmin,Liu, Yanyan,He, Mingyuan,et al. Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reactions[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2019,58(4):946.
APA	Tang, Zhongmin,Liu, Yanyan,He, Mingyuan,&Bu, Wenbo.(2019).Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reactions.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,58(4),946.
MLA	Tang, Zhongmin,et al."Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reactions".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 58.4(2019):946.