Fine-Grained Parcellation of the Macaque Nucleus Accumbens by High-Resolution Diffusion Tensor Tractography

doi:10.3389/fnins.2019.00709

	Fine-Grained Parcellation of the Macaque Nucleus Accumbens by High-Resolution Diffusion Tensor Tractography
	Xia, Xiaoluan 1,2; Fan, Lingzhong 2,3; Hou, Bing2,4 ; Zhang, Baogui 2; Zhang, Dan 5; Cheng, Chen 1,2; Deng, Hongxia 1; Dong, Yunyun 1; Zhao, Xudong 6; Li, Haifang 1
刊名	FRONTIERS IN NEUROSCIENCE
	2019-07-10
卷号	13 页码:12
关键词	neuroimaging connectivity ventral striatum medial shell lateral shell
ISSN号	1662-453X
DOI	10.3389/fnins.2019.00709
通讯作者	Li, Haifang(lihaifang@tyut.edu.cn) ; Jiang, Tanzi(jiangtz@nlpr.ia.ac.cn)
英文摘要	Limited in part by the spatial resolution of typical in vivo magnetic resonance imaging (MRI) data, recent neuroimaging studies have only identified a connectivity-based shell-core-like partitioning of the nucleus accumbens (Acb) in humans. This has hindered the process of making a more refined description of the Acb using non-invasive neuroimaging technologies and approaches. In this study, high-resolution ex vivo macaque brain diffusion MRI data were acquired to investigate the tractography-based parcellation of the Acb. Our results identified a shell-core-like partitioning in macaques that is similar to that in humans as well as an alternative solution that subdivided the Acb into four parcels, the medial shell, the lateral shell, the ventral core, and the dorsal core. Furthermore, we characterized the specific anatomical and functional connectivity profiles of these Acb subregions and generalized their specialized functions to establish a fine-grained macaque Acb brainnetome atlas. This atlas should be helpful in neuroimaging, stereotactic surgery, and comparative neuroimaging studies to reveal the neurophysiological substrates of various diseases and cognitive functions associated with the Acb.
资助项目	National Natural Science Foundation of China[91432302] ; National Natural Science Foundation of China[31620103905] ; National Natural Science Foundation of China[81501179] ; National Natural Science Foundation of China[61472270] ; Frontier Science Program of the Chinese Academy of Sciences[QYZDJ-SSW-SMC019] ; National Key R&D Program of China[2017YFA0105203] ; Beijing Municipal Science and Technology Commission[Z161100000216152] ; Beijing Municipal Science and Technology Commission[Z161100000216139] ; Natural Science Foundation of Shanxi Province of China[201801D121135] ; Guangdong Pearl River Talents Plan[2016ZT06S220]
WOS关键词	CONNECTIVITY-BASED PARCELLATION ; HIPPOCAMPAL-FORMATION ; CORTICAL PROJECTIONS ; EFFERENT PROJECTIONS ; VENTRAL STRIATUM ; PROFILES REVEAL ; FRONTAL-CORTEX ; RHESUS-MONKEY ; BRAIN-AREAS ; SHELL
WOS研究方向	Neurosciences & Neurology
语种	英语
出版者	FRONTIERS MEDIA SA
WOS记录号	WOS:000474798200001
资助机构	National Natural Science Foundation of China ; Frontier Science Program of the Chinese Academy of Sciences ; National Key R&D Program of China ; Beijing Municipal Science and Technology Commission ; Natural Science Foundation of Shanxi Province of China ; Guangdong Pearl River Talents Plan
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/26861]
专题	中国科学院自动化研究所
通讯作者	Li, Haifang; Jiang, Tanzi
作者单位	1.Taiyuan Univ Technol, Coll Informat & Comp, Jinzhong, Peoples R China 2.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing, Peoples R China 5.Tsinghua Univ, Ctr Biomed Anal, Core Facil, Beijing, Peoples R China 6.Chinese Acad Sci, Stale Key Lab Brain & Cognit Sci, Inst Biophys, Beijing, Peoples R China 7.Chinese Acad Sci, Ctr Excellence Brain Sci & Intelligence Technol, Inst Automat, Beijing, Peoples R China 8.Univ Elect Sci & Technol China, Clin Hosp, Chengdu Brain Sci Inst, MOE Key Lab Neuroinformat, Chengdu, Sichuan, Peoples R China 9.Univ Queensland, Queensland Brain Inst, Brisbane, Qld, Australia
推荐引用方式 GB/T 7714	Xia, Xiaoluan,Fan, Lingzhong,Hou, Bing,et al. Fine-Grained Parcellation of the Macaque Nucleus Accumbens by High-Resolution Diffusion Tensor Tractography[J]. FRONTIERS IN NEUROSCIENCE,2019,13:12.
APA	Xia, Xiaoluan.,Fan, Lingzhong.,Hou, Bing.,Zhang, Baogui.,Zhang, Dan.,...&Jiang, Tanzi.(2019).Fine-Grained Parcellation of the Macaque Nucleus Accumbens by High-Resolution Diffusion Tensor Tractography.FRONTIERS IN NEUROSCIENCE,13,12.
MLA	Xia, Xiaoluan,et al."Fine-Grained Parcellation of the Macaque Nucleus Accumbens by High-Resolution Diffusion Tensor Tractography".FRONTIERS IN NEUROSCIENCE 13(2019):12.