Concept and Development of Framework Nucleic Acids

doi:10.1021/jacs.8b10529

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	Concept and Development of Framework Nucleic Acids
	Ge, ZL ; Gu, HZ ; Li, Q ; Fan, CH
刊名	JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
	2018
卷号	140 期号:51 页码:17808-17819
关键词	DNA ORIGAMI NANOSTRUCTURES TARGETED TRANSPORT BUILDING-BLOCKS FOLDING DNA RNA DESIGN ARRAYS GROWTH NANOPARTICLES COMPLEXES
ISSN号	0002-7863
DOI	10.1021/jacs.8b10529
文献子类	期刊论文
英文摘要	The blooming field of structural DNA nanotechnology harnessing the material properties of nucleic acids has attracted widespread interest. The exploitation of the precise and programmable Watson- Crick base pairing of DNA or RNA has led to the development of exquisite nucleic acid nanostructures from one to three dimensions. The advances of computer-aided tools facilitate automated design of DNA nanostructures with various sizes and shapes. Especially, the construction of shell or skeleton DNA frameworks, or more recently dubbed "framework nucleic acids" (FNAs) provides a means to organize molecules or nanoparticles with nanometer precision. The intrinsic biological properties and tailorable functionalities of FNAs hold great promise for physical, chemical, and biological applications. This Perspective highlights state-of-the-art design and construction, of precisely assembled FNAs, and outlines the challenges and opportunities for exploiting the structural potential of FNAs for translational applications.
语种	英语
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/30882]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位	1.Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Inst Mol Med, Shanghai 200240, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai Synchrotron Radiat Facil, Div Phys Biol & Bioimaging Ctr, Shanghai 201800, Peoples R China 3.Fudan Univ, Inst Biomed Sci, Ctr Biotechnol & Biomed Engn, Shanghai 200032, Peoples R China 4.Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China
推荐引用方式 GB/T 7714	Ge, ZL,Gu, HZ,Li, Q,et al. Concept and Development of Framework Nucleic Acids[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2018,140(51):17808-17819.
APA	Ge, ZL,Gu, HZ,Li, Q,&Fan, CH.(2018).Concept and Development of Framework Nucleic Acids.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,140(51),17808-17819.
MLA	Ge, ZL,et al."Concept and Development of Framework Nucleic Acids".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 140.51(2018):17808-17819.