A facile asymmetric route to (-)-aphanorphine

	A facile asymmetric route to (-)-aphanorphine
	Zhai HB(翟宏斌) ; Luo SJ(罗盛军) ; Ye CF(叶承峰) ; Ma YX(马永祥)
刊名	J. Org. Chem.
	2003
卷号	68 期号:21 页码:8268-8271
ISSN号	0022-3263
其他题名	(-)-Aphanorphine不对称合成的一种简洁路线
通讯作者	翟宏斌
英文摘要	8 O-Methylaphanorphine was synthesized from 4-methoxyphenylacetaldehyde in 36% overall yield and in nine steps, featuring the formation of ring B via a Friedel-Crafts alkylative cyclization with the concomitant stereospecific introduction of the benzylic quaternary carbon center, The current work constitutes an efficient enantioselective formal synthesis of 3-benzazepine marine alkaloid (-)-aphanorphine.
学科主题	天然产物有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/jo0348726
语种	英语
WOS记录号	WOS:000185907100050
公开日期	2013-06-19
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/25571]
专题	上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式 GB/T 7714	Zhai HB,Luo SJ,Ye CF,et al. A facile asymmetric route to (-)-aphanorphine[J]. J. Org. Chem.,2003,68(21):8268-8271.
APA	翟宏斌,罗盛军,叶承峰,&马永祥.(2003).A facile asymmetric route to (-)-aphanorphine.J. Org. Chem.,68(21),8268-8271.
MLA	翟宏斌,et al."A facile asymmetric route to (-)-aphanorphine".J. Org. Chem. 68.21(2003):8268-8271.