A new synthesis of tanikolide

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	A new synthesis of tanikolide
	Zhai HB(翟宏斌) ; Chen QS(陈庆寿) ; Zhao JR(赵景瑞) ; Luo SJ(罗盛军) ; Jia XS(贾学顺)
刊名	Tetrahedron Lett.
	2003
卷号	44 期号:14 页码:2893-2894
ISSN号	0040-4039
其他题名	Tanikolide 的一种新合成方法
通讯作者	翟宏斌
英文摘要	We report a concise synthesis of tanikolide 1, which was obtained from ethyl 2-oxocyclopentanecarboxylate in four steps: alkylation, Baeyer-Villiger reaction, saponification, and reduction/lactonization, in 70% overall yield. Our strategy should be suitable for the preparation of 1 in multigram or larger quantities. The net result of the last two steps(i.e. saponification and reduction/lactonization)is an efficient reduction of the ethoxycarbonyl of 3 while keeping the lactone carbonyl intact.
学科主题	天然产物有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/S0040-4039(03)00450-7
语种	英语
WOS记录号	WOS:000181893800029
公开日期	2013-06-19
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/25563]
专题	上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式 GB/T 7714	Zhai HB,Chen QS,Zhao JR,et al. A new synthesis of tanikolide[J]. Tetrahedron Lett.,2003,44(14):2893-2894.
APA	翟宏斌,陈庆寿,赵景瑞,罗盛军,&贾学顺.(2003).A new synthesis of tanikolide.Tetrahedron Lett.,44(14),2893-2894.
MLA	翟宏斌,et al."A new synthesis of tanikolide".Tetrahedron Lett. 44.14(2003):2893-2894.