Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization

CORC > 上海硅酸盐研究所 > 中国科学院上海硅酸盐研究所 > 生物材料与组织工程研究中心 > 期刊论文

	Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization
	Ting Cui ; Liu XY(刘宣勇) ; Zhu YJ(朱英杰) ; Feng Chen ; Zhao Ma
刊名	Journal of Colloid and Interface Science
	2011-08-12
卷号	359 页码:371-379
ISSN号	0021-9797
其他题名	Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization
通讯作者	朱英杰
中文摘要	Amorphous calcium phosphate (ACP) has been recognized as an attractive biomaterial due to its bioactivity and biocompatibility. Electrospinning is a simple and low-cost way to fabricate polymer fibers. In this study, ACP nanoparticles with diameters ranging from 20 to 80 nm were synthesized using a simple precipitation method. ACP nanoparticles were hybridized with poly(D,L-lactic acid) (PDLLA) to form ACP/PDLLA composite nanofibers by electrospinning, and different architectures including the nanofibrous mesh and tube consisting of ACP/PDLLA composite nanofibers were obtained and characterized. The biomineralization and cytocompatibility of as-prepared ACP/PDLLA composite nanofibers were evaluated in vitro. Osteoblast-like MG63 cells were seeded on the ACP/PDLLA composite nanofiber meshes to perform the cytocompatibility evaluation. The ACP/PDLLA composite nanofibers exhibited a fast mineralization behavior in the simulated body fluid. The attachment of MG63 cells and cytotoxicity of ACP/ PDLLA composite nanofibers were also evaluated, and the experiments indicated good biocompatibility and bioactivity of ACP/PDLLA composite nanofibers.
学科主题	生物材料
收录类别	SCI收录
公开日期	2012-07-04
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/960]
专题	上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文
推荐引用方式 GB/T 7714	Ting Cui,Liu XY,Zhu YJ,et al. Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization[J]. Journal of Colloid and Interface Science,2011,359:371-379.
APA	Ting Cui,刘宣勇,朱英杰,Feng Chen,&Zhao Ma.(2011).Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization.Journal of Colloid and Interface Science,359,371-379.
MLA	Ting Cui,et al."Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization".Journal of Colloid and Interface Science 359(2011):371-379.