Synthesis of 5(6)-dihydro-OSW-1 by using the intact skeleton of tigogenin

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	Synthesis of 5(6)-dihydro-OSW-1 by using the intact skeleton of tigogenin
	Chen LJ(陈丽君) ; Xu QH(许启海) ; Huang H(黄浩) ; Lin JR(林静容) ; Tian WS(田伟生)
刊名	Tetrahedron Lett.
	2007
卷号	48 期号:19 页码:3475-3477
ISSN号	0040-4039
其他题名	利用剑麻皂甙元完整骨架合成5(6)-dihydro-OSW-1
通讯作者	田伟生
英文摘要	5(6)-Dihydro-OSW-1 (1), an analogue of OSW-1 with the potent anticancer activity, was synthesized by utilizing the intact skeleton of tigogenin in 13 steps in 9.0% overall yield. This synthesis demonstrated an effective and reasonable synthetic strategy for bioactive steroids with side chains as compared with their routine synthesis. (c) 2007 Elsevier Ltd. All rights reserved.
学科主题	天然产物有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.tetlet.2007.03.001
语种	英语
WOS记录号	WOS:000246611400033
公开日期	2013-03-11
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/23864]
专题	上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式 GB/T 7714	Chen LJ,Xu QH,Huang H,et al. Synthesis of 5(6)-dihydro-OSW-1 by using the intact skeleton of tigogenin[J]. Tetrahedron Lett.,2007,48(19):3475-3477.
APA	陈丽君,许启海,黄浩,林静容,&田伟生.(2007).Synthesis of 5(6)-dihydro-OSW-1 by using the intact skeleton of tigogenin.Tetrahedron Lett.,48(19),3475-3477.
MLA	陈丽君,et al."Synthesis of 5(6)-dihydro-OSW-1 by using the intact skeleton of tigogenin".Tetrahedron Lett. 48.19(2007):3475-3477.