Sesquiterpenoids from Ligularia virgaurea spp. Oligocephala

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室

	Sesquiterpenoids from Ligularia virgaurea spp. Oligocephala
	Shi YP(师彦平); Shi YP(师彦平)
刊名	Tetrohedron
	2005
卷号	61 页码:10529–10535
关键词	Ligularia virgaurea spp. oligocephala Sesquiterpenoids Eremophilane
ISSN号	0040-4020
通讯作者	师彦平
中文摘要	Four novel eremophilane-type sesquiterpene lactones, 6b,10a-dihydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (1), 6b-acetyl-2-oxoeremophila-1(10),7(11), 8(9)-trien-12,8-olide (2), 6b,8b-diacetyl-2 oxoeremophila-1(10),7(11)-dien-12,8-olide (3), dimeric eremophilane ligulolide B (5), and known sesquiterpenoid, 6b,8a-diacetyleremophila-1(10),7(11)-dien-12,8-olide (4), were isolated from an extract of the whole plant of Ligularia virgaurea spp. oligocephala. The structure of 1 was confirmed by NMR spectra and single crystal X-ray crystallography investigation, as well as 2, 3, and 5 were elucidated by spectroscopic methods including 1D and 2D NMR spectra. A discussion of biogenesis of 5 was described. Cytotoxicities of compound 1 were measured in vitro against selected cancer cells human promyelocytic leukemia (HL-60), human ovarian (HO-8910) and human lung epithehial (A-549).
学科主题	分析化学 ; 药物化学
收录类别	SCI
资助信息	the National Natural Science Foundation of China (NSFC 20021001;20372029;20475057)
语种	英语
WOS记录号	WOS:000232572000013
公开日期	2013-03-01
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/2498]
专题	兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
通讯作者	Shi YP(师彦平); Shi YP(师彦平)
推荐引用方式 GB/T 7714	Shi YP,Shi YP. Sesquiterpenoids from Ligularia virgaurea spp. Oligocephala[J]. Tetrohedron,2005,61:10529–10535.
APA	师彦平,&师彦平.(2005).Sesquiterpenoids from Ligularia virgaurea spp. Oligocephala.Tetrohedron,61,10529–10535.
MLA	师彦平,et al."Sesquiterpenoids from Ligularia virgaurea spp. Oligocephala".Tetrohedron 61(2005):10529–10535.