Prenatal exposures to persistent organic pollutants as measured in cord blood and meconium from three localities of Zhejiang, China

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	Prenatal exposures to persistent organic pollutants as measured in cord blood and meconium from three localities of Zhejiang, China
	Zhao, Gaofeng ; Xu, Ying ; Li, Wen ; Han, Guanggen ; Ling, Bo
刊名	SCIENCE OF THE TOTAL ENVIRONMENT
	2007-05-15
卷号	377 期号:2-3 页码:179-191
关键词	cord blood fetus meconium organochlorine pesticides persistent organic pollutants polychlorinated biphenyls prenatal exposure
ISSN号	0048-9697
通讯作者	Xu, Y, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
中文摘要	Prenatal exposures to persistent organic pollutants were assessed using the levels of PCBs and organochlorine pesticides (OCPs) measured in cord blood and meconium samples from Luqiao and two other localities of the Zhejiang province in China. Luqiao is a town with the largest site for disassembly of PCB-containing obsolete transformers and electrical waste in China. The other two localities Pingqiao (100 km NW of Luqiao) and Lin'an (500 km NW of Luqiao) are towns without known electronic or electrical waste sites. A total of 23 PCB congeners (including 12 dioxin-like) and 6 OCPs were measured using the traditional GC-mu ECD technique. Micro-EROD bioassay was additionally used to measure TCDD-based TEQ levels of the 12 dioxin-like PCBs. Significant correlations were found between the TEQs measured by the two methods, supporting the application of micro-EROD as a practical toot for complementing the chemical analysis. The data showed that beta-HCH, p,p'-DDE, and 6 PCB congeners (101, 138 153, 180, 183, and 187) were the predominant pollutants, with PCB 138 being the best indicator (predictor) for total PCB levels. Cord blood and meconium from Luqiao have higher levels of PCBs than those from the other two localities, suggesting that a disassembly site for electronic and electric waste would provide an environment for greater exposure to these chemicals. The cord blood or meconium levels of beta-HCH, though likewise considerably high, were comparable in the three localities. Similar findings were observed for p,p'-DDE. Pollution by these OCPs might have come from past use of agricultural pesticides in the three localities. (c) 2007 Published by Elsevier B.V.
英文摘要	Prenatal exposures to persistent organic pollutants were assessed using the levels of PCBs and organochlorine pesticides (OCPs) measured in cord blood and meconium samples from Luqiao and two other localities of the Zhejiang province in China. Luqiao is a town with the largest site for disassembly of PCB-containing obsolete transformers and electrical waste in China. The other two localities Pingqiao (100 km NW of Luqiao) and Lin'an (500 km NW of Luqiao) are towns without known electronic or electrical waste sites. A total of 23 PCB congeners (including 12 dioxin-like) and 6 OCPs were measured using the traditional GC-mu ECD technique. Micro-EROD bioassay was additionally used to measure TCDD-based TEQ levels of the 12 dioxin-like PCBs. Significant correlations were found between the TEQs measured by the two methods, supporting the application of micro-EROD as a practical toot for complementing the chemical analysis. The data showed that beta-HCH, p,p'-DDE, and 6 PCB congeners (101, 138 153, 180, 183, and 187) were the predominant pollutants, with PCB 138 being the best indicator (predictor) for total PCB levels. Cord blood and meconium from Luqiao have higher levels of PCBs than those from the other two localities, suggesting that a disassembly site for electronic and electric waste would provide an environment for greater exposure to these chemicals. The cord blood or meconium levels of beta-HCH, though likewise considerably high, were comparable in the three localities. Similar findings were observed for p,p'-DDE. Pollution by these OCPs might have come from past use of agricultural pesticides in the three localities. (c) 2007 Published by Elsevier B.V.
学科主题	Environmental Sciences
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Environmental Sciences
研究领域[WOS]	Environmental Sciences & Ecology
关键词[WOS]	POLYCHLORINATED-BIPHENYLS PCBS ; FETAL EXPOSURE ; UMBILICAL-CORD ; ORGANOCHLORINE PESTICIDES ; ENVIRONMENTAL EXPOSURE ; POSTNATAL EXPOSURE ; CHEMICAL-ANALYSIS ; NORTHERN QUEBEC ; BREAST-MILK ; CHILDREN
收录类别	SCI
语种	英语
WOS记录号	WOS:000247024600007
公开日期	2010-10-13
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/152342/8560]
专题	水生生物研究所_中科院水生所知识产出（2009年前）_期刊论文
作者单位	1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 2.Chinese Acad Sci, Ecoenvironm Sci Res Ctr, State Key Lab Environm Aquat Chem, Beijing 100085, Peoples R China 3.Zhejiang Ctr Dis Control & Prevent, Hangzhou 310009, Peoples R China 4.Chinese Ctr Dis Control & Prevent, Beijing 100050, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Gaofeng,Xu, Ying,Li, Wen,et al. Prenatal exposures to persistent organic pollutants as measured in cord blood and meconium from three localities of Zhejiang, China[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2007,377(2-3):179-191.
APA	Zhao, Gaofeng,Xu, Ying,Li, Wen,Han, Guanggen,&Ling, Bo.(2007).Prenatal exposures to persistent organic pollutants as measured in cord blood and meconium from three localities of Zhejiang, China.SCIENCE OF THE TOTAL ENVIRONMENT,377(2-3),179-191.
MLA	Zhao, Gaofeng,et al."Prenatal exposures to persistent organic pollutants as measured in cord blood and meconium from three localities of Zhejiang, China".SCIENCE OF THE TOTAL ENVIRONMENT 377.2-3(2007):179-191.