NONCODE: an integrated knowledge database of non-coding RNAs

doi:10.1093/nar/gki041

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	NONCODE: an integrated knowledge database of non-coding RNAs
	Liu, CN ; Bai, BY ; Skogerbo, G ; Cai, L ; Deng, W ; Zhang, Y ; Bu, DB ; Zhao, Y ; Chen, RS
刊名	NUCLEIC ACIDS RESEARCH
	2005
卷号	33 页码:D112-D115
ISSN号	0305-1048
DOI	10.1093/nar/gki041
英文摘要	NONCODE is an integrated knowledge database dedicated to non-coding RNAs (ncRNAs), that is to say, RNAs that function without being translated into proteins. All ncRNAs in NONCODE were filtered automatically from literature and GenBank, and were later manually curated. The distinctive features of NONCODE are as follows: (i) the ncRNAs in NONCODE include almost all the types of ncRNAs, except transfer RNAs and ribosomal RNAs. (ii) All ncRNA sequences and their related information (e.g. function, cellular role, cellular location, chromosomal information, etc.) in NONCODE have been confirmed manually by consulting relevant literature: more than 80% of the entries are based on experimental data. (iii) Based on the cellular process and function, which a given ncRNA is involved in,we introduced a novel classification system, labeled process function class, to integrate existing classification systems. (iv) In addition, some 1100 ncRNAs have been grouped into nine other classes according to whether they are specific to gender or tissue or associated with tumors and diseases, etc. (v) NONCODE provides a user-friendly interface, a visualization platform and a convenient search option, allowing efficient recovery of sequence, regulatory elements in the flanking sequences, secondary structure, related publications and other information. The first release of NONCODE (v1.0) contains 5339 non-redundant sequences from 861 organisms, including eukaryotes, eubacteria, archaebacteria, virus and viroids. Access is free for all users through a web interface at http://noncode.bioinfo.org.cn.
WOS研究方向	Biochemistry & Molecular Biology
语种	英语
出版者	OXFORD UNIV PRESS
WOS记录号	WOS:000226524300020
内容类型	期刊论文
源URL	[http://119.78.100.204/handle/2XEOYT63/10114]
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Chen, RS
作者单位	1.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Inst Biophys, Bioinformat Lab, Beijing 100080, Peoples R China 3.Chinese Acad Sci, Comp Technol Inst, Key Lab Intelligent Informat Proc, Bioinformat Res Grp, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Liu, CN,Bai, BY,Skogerbo, G,et al. NONCODE: an integrated knowledge database of non-coding RNAs[J]. NUCLEIC ACIDS RESEARCH,2005,33:D112-D115.
APA	Liu, CN.,Bai, BY.,Skogerbo, G.,Cai, L.,Deng, W.,...&Chen, RS.(2005).NONCODE: an integrated knowledge database of non-coding RNAs.NUCLEIC ACIDS RESEARCH,33,D112-D115.
MLA	Liu, CN,et al."NONCODE: an integrated knowledge database of non-coding RNAs".NUCLEIC ACIDS RESEARCH 33(2005):D112-D115.