Single molecule spectroscopy using photothermal tuning of optical microcavities | |
GOLDSMITH, RANDALL HOWARD; HEYLMAN, KEVIN DANIEL | |
2017-01-03 | |
著作权人 | WISCONSIN ALUMNI RESEARCH FOUNDATION |
专利号 | US9535219 |
国家 | 美国 |
文献子类 | 授权发明 |
其他题名 | Single molecule spectroscopy using photothermal tuning of optical microcavities |
英文摘要 | A method comprises exposing the surface of an optical microcavity characterized by at least one resonance frequency to a sample such that a single particle or molecule from the sample adsorbs onto the surface of the microcavity; evanescently coupling a probe laser beam into the microcavity, the wavelength of the probe laser beam substantially matching the at least one resonance frequency; illuminating the surface of the microcavity with a free space pump light beam and moving the focal spot of the free space pump light beam such that the focal spot substantially overlaps with the single particle/molecule; and detecting light from the probe laser beam. The wavelength of the free space pump light beam generates sufficient heat via energy absorbed by the single particle/molecule to induce a shift in the at least one resonance frequency, thereby providing a change in an optical characteristic of the detected light. |
公开日期 | 2017-01-03 |
申请日期 | 2015-02-13 |
状态 | 授权 |
内容类型 | 专利 |
源URL | [http://ir.opt.ac.cn/handle/181661/37800] ![]() |
专题 | 半导体激光器专利数据库 |
作者单位 | WISCONSIN ALUMNI RESEARCH FOUNDATION |
推荐引用方式 GB/T 7714 | GOLDSMITH, RANDALL HOWARD,HEYLMAN, KEVIN DANIEL. Single molecule spectroscopy using photothermal tuning of optical microcavities. US9535219. 2017-01-03. |
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