ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN

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	ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN
	Xin Xuelei; Wang Qi; Aisa Haji Akber; Wang Hanqing
刊名	Journal of Food Biochemistry
	2010
卷号	34 期号:4 页码:811-824
ISSN号	1458884
通讯作者	Aisa, HA
英文摘要	Nigella glandulifera Freyn, an annual plant species of the family Ranunculaceae, served as a traditional Uigur medicine and food. Many researchers have reported that Nigella sativa L., which is the same genus with it, has an antidiabetic effect, the seeds oil was an activity component used as a kind of function food. In the present study, the difference of oil extract between n-hexane and petroleum ether respectively from the seeds of Nigella glandulifera Freyn were analyzed by gas chromatography-mass spectrometry, all of them can inhibit protein tyrosine phosphatase 1B (PTP1B) with half maximal inhibitory concentration values of 33.15 ± 0.77 and 18.50 ± 0.52 μg/mL, respectively. They have different binding sites with PTP1B. Lastly, inhibited ability of PTP1B and that of TCPTP were compared; all of them have shown some selectivity.
学科主题	Biochemistry & Molecular Biology ; Food Science & Technology
收录类别	SCI
WOS记录号	WOS:000280643000008
公开日期	2012-11-29
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/1823]
专题	新疆理化技术研究所_资源化学研究室
作者单位	Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China;Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Peoples R China;Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China;Chinese Acad Sci, Drug Discovery & Design Ctr, State Key Lab Drug Res, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Xin Xuelei,Wang Qi,Aisa Haji Akber,et al. ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN[J]. Journal of Food Biochemistry,2010,34(4):811-824.
APA	Xin Xuelei,Wang Qi,Aisa Haji Akber,&Wang Hanqing.(2010).ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN.Journal of Food Biochemistry,34(4),811-824.
MLA	Xin Xuelei,et al."ANTIDIABETES PROPERTIES OF n-HEXANE AND PETROLEUM ETHER EXTRACTS FROM SEEDS OF NIGELLA GLANDULIFERA FREYN".Journal of Food Biochemistry 34.4(2010):811-824.