Effect of Complexation on the Accumulation and Elimination Kinetics of Cadmium and Ciprofloxacin in the Earthworm Eisenia fetida

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Effect of Complexation on the Accumulation and Elimination Kinetics of Cadmium and Ciprofloxacin in the Earthworm Eisenia fetida
	Wen, Bei ; Huang, Rixiang ; Wang, Peng ; Zhou, Yanping ; Shan, Xiao-quan ; Zhang, Shuzhen
刊名	ENVIRONMENTAL SCIENCE & TECHNOLOGY
	2011-05-15
卷号	45 期号:10 页码:4339—4345
中文摘要	Land application of solid wastes leads to the accumulation of both metals and antimicrobials in soils. To understand the effects of metal and antibiotic interaction on their accumulation by the earthworm Eisenia fetida, uptake and elimination kinetics and subcellular distribution of cadmium (Cd) and ciprofloxacin (CIP) were determined. The kinetics was accurately described by a one-compartment first-order kinetic model. Bioaccumulation kinetics and subcellular distribution of CIP were not affected by Cd addition. However, Cd exhibited different metabolic and subcellular distribution patterns. With CIP, Cd uptake flux and elimination rate constants were about 2.2 and 9.8 times, respectively, those without CIP. In the presence of CIP, Cd redistributed from fractions D (associated with granules) and E (associated with tissue fragments and cell membranes) to fraction C (associated with cytosol). Without CIP, Cd in fraction C could not be excreted, whereas with CIP, Cd in fraction C was significantly excreted, and the excretion rate constant was consistent with that of CIP. A good relationship was found between CIP and Cd in earthworms during uptake and elimination periods (p < 0.01). Our results indicated that the Cd CIP complex may be taken up, stored, and eliminated by earthworms.
WOS记录号	WOS:000290426900026
公开日期	2012-10-18
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/7061]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Wen, Bei,Huang, Rixiang,Wang, Peng,et al. Effect of Complexation on the Accumulation and Elimination Kinetics of Cadmium and Ciprofloxacin in the Earthworm Eisenia fetida[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2011,45(10):4339—4345.
APA	Wen, Bei,Huang, Rixiang,Wang, Peng,Zhou, Yanping,Shan, Xiao-quan,&Zhang, Shuzhen.(2011).Effect of Complexation on the Accumulation and Elimination Kinetics of Cadmium and Ciprofloxacin in the Earthworm Eisenia fetida.ENVIRONMENTAL SCIENCE & TECHNOLOGY,45(10),4339—4345.
MLA	Wen, Bei,et al."Effect of Complexation on the Accumulation and Elimination Kinetics of Cadmium and Ciprofloxacin in the Earthworm Eisenia fetida".ENVIRONMENTAL SCIENCE & TECHNOLOGY 45.10(2011):4339—4345.