Activity recall in a visual cortical ensemble

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	Activity recall in a visual cortical ensemble
	Poo, Mu-ming
刊名	NATURE NEUROSCIENCE
	2012
卷号	15 期号:3 页码:449-U141
关键词	BARREL CORTEX SYNAPTIC MODIFICATION CORRELATED ACTIVITY PREFRONTAL CORTEX HUMAN HIPPOCAMPUS AUDITORY-CORTEX SINGLE NEURONS OWL MONKEYS PLASTICITY SEQUENCES
ISSN号	1097-6256
通讯作者	Poo, MM (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Neurosci, Inst Neurosci, Shanghai, Peoples R China,mpoo@berkeley.edu
英文摘要	Cue-triggered recall of learned temporal sequences is an important cognitive function that has been attributed to higher brain areas. Here recordings in both anesthetized and awake rats demonstrate that after repeated stimulation with a moving spot that evoked sequential firing of an ensemble of primary visual cortex (V1) neurons, just a brief flash at the starting point of the motion path was sufficient to evoke a sequential firing pattern that reproduced the activation order evoked by the moving spot. The speed of recalled spike sequences may reflect the internal dynamics of the network rather than the motion speed. In awake rats, such recall was observed during a synchronized ('quiet wakeful') brain state having large-amplitude, low-frequency local field potential (LFP) but not in a desynchronized ('active') state having low-amplitude, high-frequency LFP. Such conditioning-enhanced, cue-evoked sequential spiking of a V1 ensemble may contribute to experience-based perceptual inference in a brain state-dependent manner.
学科主题	Neurosciences & Neurology
收录类别	SCI
资助信息	973 Program[2011CBA00400]; SSSTC[GJHZ0902]; Chinese Academy of Sciences[KSCX2-YW-R-29]; Howard Hughes Medical Institute; US National Institutes of Health[NS036999]
语种	英语
公开日期	2012-07-13
内容类型	期刊论文
源URL	[http://ir.sibs.ac.cn/handle/331001/1497]
专题	上海神经科学研究所_神经所(总) 上海神经科学研究所_神经可塑性研究组
推荐引用方式 GB/T 7714	Poo, Mu-ming. Activity recall in a visual cortical ensemble[J]. NATURE NEUROSCIENCE,2012,15(3):449-U141.
APA	Poo, Mu-ming.(2012).Activity recall in a visual cortical ensemble.NATURE NEUROSCIENCE,15(3),449-U141.
MLA	Poo, Mu-ming."Activity recall in a visual cortical ensemble".NATURE NEUROSCIENCE 15.3(2012):449-U141.