A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata

	A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata
	Shen, P ; Wang, SL ; Liu, XK ; Yang, CR ; Cai, B ; Yao, XS
刊名	CHINESE CHEMICAL LETTERS
	2002-09-01
卷号	13 期号:9 页码:851-854
关键词	Dioscorea deltoidea Wall var. Orbiculata orbiculatoside B Pyricularia oryzae cytotoxic
ISSN号	1001-8417
通讯作者	yaoxinsheng@hotmail.com
英文摘要	Bioactivity-guided fractionation led to the isolation of a new steroidal saponin, orbiculatoside B, together with a pair of furostanol saponins, protobioside and methyl protobioside, from the fresh rhizomes of Dioscorea deltoidea Wall var. orbiculata. The new Compound was identified to be isonarthogenin 3 - O - alpha - L - rhamnopyranosyl (1-->2) - [alpha - L - rhamnopyranosyl - (1 --> 4)] - beta - D - glucopyranoside by various NMR techniques in combination with chemical methods. The three saponins showed strong activity against Pyricularia oryzae, and were cytotoxic to cancer cell line K562, HCT-15, A549, and A2780a in vitro.
学科主题	Chemistry, Multidisciplinary
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
收录类别	SCI
语种	英语
WOS记录号	WOS:000178054700015
公开日期	2012-07-25
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/14361]
专题	昆明植物研究所_离退休
作者单位	1.Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Beijing Inst Biomed, Beijing 100091, Peoples R China
推荐引用方式 GB/T 7714	Shen, P,Wang, SL,Liu, XK,et al. A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata[J]. CHINESE CHEMICAL LETTERS,2002,13(9):851-854.
APA	Shen, P,Wang, SL,Liu, XK,Yang, CR,Cai, B,&Yao, XS.(2002).A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata.CHINESE CHEMICAL LETTERS,13(9),851-854.
MLA	Shen, P,et al."A new steroidal saponin from Dioscorea deltoidea Wall var. orbiculata".CHINESE CHEMICAL LETTERS 13.9(2002):851-854.