Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata
	Luo, DQ ; Zhang, X ; Tian, X ; Liu, JK
刊名	ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
	2004-05-01
卷号	59 期号:5-6 页码:421-426
关键词	Tripterygium wilfordii insecticidal compounds Mythimna separata
ISSN号	0939-5075
英文摘要	In the course of screening for novel naturally occurring insecticides from plants, the ethanol extract of the root bark of Tripterygium wilfordii Hook f. was found to show insecticidal activity against larvae of Mythimna separata Walker. Three active compounds were isolated by bioassay-guided fractionation of the extract and characterized as triptolide (1), triptonide (2) and euonine (3) by IR, H-1 and C-13 NMR and mass spectral analysis. Compounds 1 and 2 showed strong contact activity against 3(rd) or 5(th) larvae of M. separata (LD50 1.6 mug/insect for 1, 2.9 mug/insect for 2, no contact activity for 3; LD50 is the lethal dose for 50% mortality). The antifeedant activity against the 3(rd) larvae of M. separata after a 24-h treatment was demonstrated; 1, 2 and 3 gave EC50 (effective concentration causing 50% antifeedance) values of 0.25, 0.35 and 0.02 mm, respectively. 1 and 2 were inferior to the positive control represented by toosendanin (12alpha-acetoxyamoorastatin), 3 was superior to toosendanin. For the ingested toxicity against M. separata, 1 had the more potent activity with an KD50 value of 13.5 mug/g (insect body weight) than toosendanin. This is the first report on insecticidal activity of these three compounds.
学科主题	Biochemistry & Molecular Biology; Pharmacology & Pharmacy
类目[WOS]	Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
研究领域[WOS]	Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
关键词[WOS]	TERPENOIDS
收录类别	SCI
语种	英语
WOS记录号	WOS:000222866600024
公开日期	2012-07-25
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/14455]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 2.NW Sci Tech Univ Agr & Forestry, Pesticide Res Ctr, Yangling 712100, Shaanxi, Peoples R China 3.Lanzhou Univ, Natl Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Luo, DQ,Zhang, X,Tian, X,et al. Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata[J]. ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES,2004,59(5-6):421-426.
APA	Luo, DQ,Zhang, X,Tian, X,&Liu, JK.(2004).Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata.ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES,59(5-6),421-426.
MLA	Luo, DQ,et al."Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata".ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES 59.5-6(2004):421-426.