Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases

	Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases
	Liu, Hong-tao 2; Huang, Pei 1; Ma, Pan 2; Liu, Qi-shun 1; Yu, Chao 1; Du, Yu-guang 2
刊名	acta pharmacologica sinica
	2011-04-01
卷号	32 期号:4 页码:478-486
关键词	anti-inflammatory agents arteriosclerosis lipopolysaccharides endothelial cells chemokine MAPK phosphatidylinositol 3-kinase interleukin-8 NF-kappa B chitosan oligosaccharides
ISSN号	1671-4083
通讯作者	yuc ; 杜昱光
产权排序	1,1
中文摘要	chitosan oligosaccharides suppress lps-induced il-8 expression in human umbilical vein endothelial cells through blockade of p38 and akt protein kinases
英文摘要	aim: to investigate whether and how cos inhibited il-8 production in lps-induced human umbilical vein endothelial cells (huvecs).
学科主题	物理化学
WOS标题词	science & technology ; physical sciences ; life sciences & biomedicine
类目[WOS]	chemistry, multidisciplinary ; pharmacology & pharmacy
研究领域[WOS]	chemistry ; pharmacology & pharmacy
关键词[WOS]	factor-kappa-b ; inhibits proinflammatory responses ; transcription factors ; intestinal-cells ; growth-factor ; cancer cells ; u937 cells ; in-vitro ; activation ; interleukin-8
收录类别	SCI
语种	英语
WOS记录号	WOS:000289194200009
公开日期	2012-07-09
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/115524]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chongqing Med Univ, Inst Life Sci, Chongqing 400016, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Liu, Hong-tao,Huang, Pei,Ma, Pan,et al. Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases[J]. acta pharmacologica sinica,2011,32(4):478-486.
APA	Liu, Hong-tao,Huang, Pei,Ma, Pan,Liu, Qi-shun,Yu, Chao,&Du, Yu-guang.(2011).Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases.acta pharmacologica sinica,32(4),478-486.
MLA	Liu, Hong-tao,et al."Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases".acta pharmacologica sinica 32.4(2011):478-486.