Amaryllidaceae Alkaloids from Lycoris radiata

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Amaryllidaceae Alkaloids from Lycoris radiata
	Feng, Tao; Wang, Yuan-Yuan; Su, Jia; Li, Yan; Cai, Xiang-Hai; Luo, Xiao-Dong
刊名	HELVETICA CHIMICA ACTA
	2011
卷号	94 期号:1 页码:178-183
关键词	NARCISSUS ALKALOIDS RACEMIC LYCORAMINE ASCORBIC-ACID GALANTHAMINE (&-)-LYCORAMINE BIOSYNTHESIS CONSTITUENTS
ISSN号	0018-019X
通讯作者	Luo, XD (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, 132 Lanhei Rd, Kunming 650204, Peoples R China
英文摘要	A phytochemical investigation on bulbs of Lycoris radiata resulted in the isolation of three new Amaryllidaceae alkaloids, named 5,6-dehydrodihydrolycorine (1), 6 beta-acetoxycrinamine (2), and (+)-8-O-acetylhomolycorine alpha-N-oxide (3), together with eleven known alkaloids, 4-14. The structures of the new alkaloids were established by means of spectroscopic methods, and the known compounds were identified by comparison of their data with those in the literature. Compound 2 showed cytotoxicity against HL-60, A-549, and MCF-7 cells, with IC(50) values of 8.1, 24.3, and 15.0 mu m, respectively.
学科主题	Chemistry
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	NARCISSUS ALKALOIDS ; RACEMIC LYCORAMINE ; ASCORBIC-ACID ; GALANTHAMINE ; (&-)-LYCORAMINE ; BIOSYNTHESIS ; CONSTITUENTS
收录类别	SCI ; IC
资助信息	National Basic Research Program of China (973 Program)[2009CB522300]; Chinese Academy of Sciences[KSCX2-YW-R-202]; National Natural Science Foundation of China
语种	英语
WOS记录号	WOS:000287374800023
公开日期	2012-04-10
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/5419]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Feng, Tao,Wang, Yuan-Yuan,Su, Jia,et al. Amaryllidaceae Alkaloids from Lycoris radiata[J]. HELVETICA CHIMICA ACTA,2011,94(1):178-183.
APA	Feng, Tao,Wang, Yuan-Yuan,Su, Jia,Li, Yan,Cai, Xiang-Hai,&Luo, Xiao-Dong.(2011).Amaryllidaceae Alkaloids from Lycoris radiata.HELVETICA CHIMICA ACTA,94(1),178-183.
MLA	Feng, Tao,et al."Amaryllidaceae Alkaloids from Lycoris radiata".HELVETICA CHIMICA ACTA 94.1(2011):178-183.