New Stable Isotope Labeling Strategy in Quaternary Ammonium-Functionalized Magnetic Nanoparticles for the Analysis of Perfluorocarboxylic Acid in Cod Liver Oil

	New Stable Isotope Labeling Strategy in Quaternary Ammonium-Functionalized Magnetic Nanoparticles for the Analysis of Perfluorocarboxylic Acid in Cod Liver Oil
	Zhang, Shijuan; Wu, Ting; Liu, Hongzhan; Li, Yanxin; You, Jinmao
刊名	FOOD ANALYTICAL METHODS
	2019
卷号	12 期号:8
关键词	Perfluorocarboxylic acid Cod liver oil Quaternary ammonium Stable isotope labeling Magnetic nanoparticles
英文摘要	Perfluorocarboxylic acids (PFCAs) in cod liver oil was analyzed for the first time using newly designed and synthesized quaternary ammonium-functionalized magnetic nanoparticles (Fe3O4@SiO2@QTA). Fe3O4@SiO2@QTA was characterized by TEM, IR, and magnetic hysteresis curve. It can interact with perfluorocarboxylic acids through electrostatic interactions, hydrogen bonding, and hydrophobic effect. Stable isotope labeling (SIL)-assisted liquid chromatography tandem mass spectrometry (LC-MS/MS) was used to evaluate the adsorption efficiency. The obtained recoveries for all compounds were in the range of 85.0-98.5%, with relative standard deviations of less than 8.1%. The sorbent amount was 20 mg. Desorption conditions were as follows: sample pH 5-7.0; desorption time, 5 min; and elution volume, 1.0 mL. The limits of detection were in the range of 1.5-20 ng/L, while the limits of quantitation were in the range of 5.0-70 ng/L. The proposed method was successfully applied to the selective adsorption of PFCAs from cod liver oil with no matrix effect observed because of the double assurance of selective adsorption and high accurate SIL strategy.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/59736]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Zhang, Shijuan,Wu, Ting,Liu, Hongzhan,et al. New Stable Isotope Labeling Strategy in Quaternary Ammonium-Functionalized Magnetic Nanoparticles for the Analysis of Perfluorocarboxylic Acid in Cod Liver Oil[J]. FOOD ANALYTICAL METHODS,2019,12(8).
APA	Zhang, Shijuan,Wu, Ting,Liu, Hongzhan,Li, Yanxin,&You, Jinmao.(2019).New Stable Isotope Labeling Strategy in Quaternary Ammonium-Functionalized Magnetic Nanoparticles for the Analysis of Perfluorocarboxylic Acid in Cod Liver Oil.FOOD ANALYTICAL METHODS,12(8).
MLA	Zhang, Shijuan,et al."New Stable Isotope Labeling Strategy in Quaternary Ammonium-Functionalized Magnetic Nanoparticles for the Analysis of Perfluorocarboxylic Acid in Cod Liver Oil".FOOD ANALYTICAL METHODS 12.8(2019).