A Computational Modelling of the Mechanical Performance of a Bioabsorbable Stent Undergoing Cyclic Loading

	A Computational Modelling of the Mechanical Performance of a Bioabsorbable Stent Undergoing Cyclic Loading
	Cui XY ; Peng K ; Liu SC ; Ren QS(任庆帅); Li GY ; Gu ZY ; Qiao AK
	2019
会议日期	JUL 15-17, 2019
会议地点	Loughborough Univ London, London, ENGLAND
关键词	Finite element analysis Absorbable stent Corrosion modelling Biomechanics
页码	67-74
英文摘要	In order to address new challenges that arise in the degradation behavior of absorbable metal stents (AMSs) in vivo, new modelling and simulation are presented in this study. A dynamic corrosion model (Model 1) considering uniform corrosion, stress corrosion mechanisms and dynamic cyclic pulse loading was proposed to simulate the stent degradation based on Continuum Damage Mechanics (CDM). A control group (Model 2) was established which only considered the mechanisms of uniform and stress corrosion. The time of stent degraded completely in Model 1 was set as a normalized time unit (100t) to illustrate the results. With the increase of time, the mass and supporting performance of the stent decreased, especially at 10t to 20t. The average von Mises Stress of the stent in the Model 1 decreases from 86.19 MPa to 48.65 MPa roughly at 5t to15t, while the average von Mises Stress in Model 2 decreases from 87.12 MPa to 50 MPa. The mass loss ratio of stents in Model 1 is always higher than that in Model 2, and the relative error of the mass loss ratio reached 14.3% at 20t. The results showed that the corrosion occurs at first in the stent struts with the highest von Mises stress. In addition, the dynamic cyclic pulse loading accelerated the degradation rate and the supporting performance loss of stent. These modelling and simulation techniques may provide new insights to in vivo AMS performance. (C) 2019 The Authors. Published by Elsevier B.V.
会议录	INTERNATIONAL CONFERENCE ON STENTS: MATERIALS, MECHANICS AND MANUFACTURING (ICS3M 2019)
资助机构	Major Project of Science and Technology of Beijing Municipal Education Commission and Type B Project of Beijing Natural Science Foundation [KZ201710005007]
语种	英语
WOS记录号	WOS:000484695700012
内容类型	会议论文
源URL	[http://dspace.imech.ac.cn/handle/311007/80461]
专题	力学研究所_职能与支撑部门
作者单位	1.Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100022, Peoples R China 2.Chinese Acad Sci, Inst Mech, 15 BeiSiHuanWest Rd, Beijing 100190, Peoples R China 3.Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 9808577, Japan
推荐引用方式 GB/T 7714	Cui XY,Peng K,Liu SC,et al. A Computational Modelling of the Mechanical Performance of a Bioabsorbable Stent Undergoing Cyclic Loading[C]. 见:. Loughborough Univ London, London, ENGLAND. JUL 15-17, 2019.