Cherenkov excited luminescence imaging induced by megavolt X-ray beams in the second near-infrared window

doi:10.1016/j.optcom.2019.05.017

	Cherenkov excited luminescence imaging induced by megavolt X-ray beams in the second near-infrared window
	Wang, Ruoxi 4; Du, Yi 4; Meng, Xiangxi 1,2,3; Lu, Yanye 7; Ren, Qiushi 2; Nie, Shuming 6; Chen, Weiqiang5 ; Li, Changhui 2; Wu, Hao 4; Zhu, Sihao 2
刊名	OPTICS COMMUNICATIONS
	2019-12-01
卷号	452 页码:417-421
关键词	Second near-infrared window Cherenkov radiation X-ray Radiotherapy
ISSN号	0030-4018
DOI	10.1016/j.optcom.2019.05.017
通讯作者	Wu, Hao(13552661030@139.com) ; Li, Changhui(chli@pku.edu.cn) ; Lu, Yanye(yanye.lu@pku.edu.cn)
英文摘要	The Cherenkov radiation induced by megavolt X-ray beams of a medical linear accelerator is highly intense in blue and ultraviolet lights. This poses a challenge for in vivo imaging, which favors longer wavelengths. However, using quantum dots with a large Stokes shift, we converted the Cherenkov photons to fluorescent photons in the second near-infrared (NIR-II) window. A system was designed to provide shielding for the NIR-II camera, and high quality NIR-II CELI signal was acquired. The NIR-II CELI of X-ray beams was shown at various depths, and the condition to trigger it was also studied. Animal experiments showed this technique could visualize the delivery of X-ray radiation in mice qualitatively. We concluded that CELI induced by megavolt X-ray beams in the NIR-II window possesses a great potential as a quality control tool in radiotherapy.
资助项目	National Key Instrumentation Development Project of China[2013YQ030651] ; National Natural Science Foundation of China (NSFC)[81421004] ; National Natural Science Foundation of China (NSFC)[61571262] ; National Natural Science Foundation of China (NSFC)[11575095] ; National Natural Science Foundation of China (NSFC)[11505012] ; Natural Science Foundation of Beijing Municipality[1184014] ; Natural Science Foundation of Beijing Municipality[1174016] ; China Postdoctoral Science Foundation[2017M620542] ; Capital's Funds for Health Improvement and Research[2018-4-1027]
WOS关键词	RADIATION
WOS研究方向	Optics
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000485790300062
资助机构	National Key Instrumentation Development Project of China ; National Natural Science Foundation of China (NSFC) ; Natural Science Foundation of Beijing Municipality ; China Postdoctoral Science Foundation ; Capital's Funds for Health Improvement and Research
内容类型	期刊论文
源URL	[http://119.78.100.186/handle/113462/132762]
专题	中国科学院近代物理研究所
通讯作者	Lu, Yanye; Li, Changhui; Wu, Hao
作者单位	1.Emory Univ, Atlanta, GA 30332 USA 2.Peking Univ, Dept Biomed Engn, Coll Engn, Beijing 100871, Peoples R China 3.Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA 4.Peking Univ, Canc Hosp & Inst, Dept Radiat Oncol, Key Lab Carcinogenesis & Translat Res,Minist Educ, Beijing 100142, Peoples R China 5.Chinese Acad Sci, Key Lab Basic Res Heavy Ion Radiat Applicat Med, Key Lab Heavy Ion Radiat Biol & Med, Inst Modern Phys, Lanzhou 730000, Gansu, Peoples R China 6.Univ Illinois, Dept Biomed Engn, Urbana, IL 61801 USA 7.Friedrich Alexander Univ Erlangen Nuremberg, Pattern Recognit Lab, D-91058 Erlangen, Germany
推荐引用方式 GB/T 7714	Wang, Ruoxi,Du, Yi,Meng, Xiangxi,et al. Cherenkov excited luminescence imaging induced by megavolt X-ray beams in the second near-infrared window[J]. OPTICS COMMUNICATIONS,2019,452:417-421.
APA	Wang, Ruoxi.,Du, Yi.,Meng, Xiangxi.,Lu, Yanye.,Ren, Qiushi.,...&Li, Ziyuan.(2019).Cherenkov excited luminescence imaging induced by megavolt X-ray beams in the second near-infrared window.OPTICS COMMUNICATIONS,452,417-421.
MLA	Wang, Ruoxi,et al."Cherenkov excited luminescence imaging induced by megavolt X-ray beams in the second near-infrared window".OPTICS COMMUNICATIONS 452(2019):417-421.