Biophysical and radiobiological aspects of heavy charged particles

doi:10.1016/j.jtusci.2015.02.014

	Biophysical and radiobiological aspects of heavy charged particles
	Desouky, Omar 1; Zhou, Guangming2
刊名	JOURNAL OF TAIBAH UNIVERSITY FOR SCIENCE
	2016-04
卷号	10 页码:187-194
关键词	Heavy charged particles Biophysics Radiobiology radiotherapy and space mission
ISSN号	1658-3655
DOI	10.1016/j.jtusci.2015.02.014
英文摘要	Heavy-ion beams have unique biophysical and radiobiological properties, such as the inverted depth dose profile compared to photon beams, relative biological effectiveness and oxygen enhancement ratio. These physical and biological properties are much more favourable than those of photon radiotherapy and can be used to treat tumours efficiently. During a long-term stay in space, astronauts will be constantly exposed to low-dose space radiation. Thus, space radiation is one of the major health-related concerns for space exploration. This review summarizes the biophysical and biological properties of charged particles and their advantage in radiotherapy. In addition, we briefly reviewed the importance of the heavy ion during space flight and how to suppress its deleterious effects. (C) 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of Taibah University.
WOS关键词	DOUBLE-STRAND BREAKS ; SPACE RADIATION ; TUMOR-THERAPY ; HUMAN-CELLS ; DNA-DAMAGE ; REPAIR ; IONS ; IMPLEMENTATION ; NEPHROPATHY ; PREVENTION
WOS研究方向	Science & Technology - Other Topics
语种	英语
出版者	TAYLOR & FRANCIS LTD
WOS记录号	WOS:000372970900003
内容类型	期刊论文
源URL	[http://119.78.100.186/handle/113462/64469]
专题	中国科学院近代物理研究所
通讯作者	Desouky, Omar
作者单位	1.Egyptian Atom Energy Author, Dept Radiat Phys, Natl Ctr Radiat Res & Technol, Cairo, Egypt 2.Chinese Acad Sci, Inst Modern Phys, Dept Space Radiobiol, Lanzhou, Peoples R China
推荐引用方式 GB/T 7714	Desouky, Omar,Zhou, Guangming. Biophysical and radiobiological aspects of heavy charged particles[J]. JOURNAL OF TAIBAH UNIVERSITY FOR SCIENCE,2016,10:187-194.
APA	Desouky, Omar,&Zhou, Guangming.(2016).Biophysical and radiobiological aspects of heavy charged particles.JOURNAL OF TAIBAH UNIVERSITY FOR SCIENCE,10,187-194.
MLA	Desouky, Omar,et al."Biophysical and radiobiological aspects of heavy charged particles".JOURNAL OF TAIBAH UNIVERSITY FOR SCIENCE 10(2016):187-194.