A small-scale investigation process for the Clostridium acetobutylicum production of butanol using high-energy carbon heavy ion irradiation

doi:10.1002/elsc.201800090

	A small-scale investigation process for the Clostridium acetobutylicum production of butanol using high-energy carbon heavy ion irradiation
	Jiang, Ting-Ting 1,2; Zhou, Xiang 1; Liang, Yan 3
刊名	ENGINEERING IN LIFE SCIENCES
	2018-10
卷号	18 页码:721-731
关键词	ABE-fermentation Applied HIRFL Biobutanol Clostridium acetobutylicum C-12(6+) heavy ion
ISSN号	1618-0240
DOI	10.1002/elsc.201800090
英文摘要	Applied heavy ion irradiation technology and butanol industrial practices as a whole have been used as a strategy for the development of an attractive alternative to petroleum-based fuels. Clostridium acetobutylicum (C. acetobutylicum) strains are well documented as fermentation strains for the production of biobutanol. However, it has been reported that solvent production inhibits the growth of these strains, and the accumulation of acetate also inhibits biomass synthesis, rendering the production of butanol from acetone-butanol-ethanol (ABE) fermentation processes economically challenging. In this manuscript, we propose the use of high-energy carbon heavy ion irradiation from the Heavy Ion Research Facility in Lanzhou (HIRFL) to obtain a culture with an increased butanol yield. Our findings suggest that the use of a high-energy C-12(6+) heavy ion irradiation dose of 45 Gy with an energy of 135 AMeV and ion pulses/levels of 10(6)-10(8) favours ABE solvent production in an irradiated strain compared with the non-irradiated strain. The strategy reported in this manuscript may contribute to the development of a cost-effective butanol fermentation process that is competitive with similar fermentation processes.
资助项目	Natural Science Foundation of Gansu provincial Sci. and Tech. Department[1506RJZA293]
WOS关键词	ETHANOL FERMENTATION ; N-BUTANOL ; HIRFL-CSR ; RESOURCES ; DISTRIBUTIONS ; POISSON ; BIOFUEL ; REACTOR ; ACID
WOS研究方向	Biotechnology & Applied Microbiology
语种	英语
出版者	WILEY
WOS记录号	WOS:000446830400003
内容类型	期刊论文
源URL	[http://119.78.100.186/handle/113462/64404]
专题	中国科学院近代物理研究所
通讯作者	Zhou, Xiang
作者单位	1.Chinese Acad Sci, Inst Modern Phys, 509 Nanchang Rd, Lanzhou 730000, Gansu, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Lanzhou Univ, Lanzhou, Gansu, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Ting-Ting,Zhou, Xiang,Liang, Yan. A small-scale investigation process for the Clostridium acetobutylicum production of butanol using high-energy carbon heavy ion irradiation[J]. ENGINEERING IN LIFE SCIENCES,2018,18:721-731.
APA	Jiang, Ting-Ting,Zhou, Xiang,&Liang, Yan.(2018).A small-scale investigation process for the Clostridium acetobutylicum production of butanol using high-energy carbon heavy ion irradiation.ENGINEERING IN LIFE SCIENCES,18,721-731.
MLA	Jiang, Ting-Ting,et al."A small-scale investigation process for the Clostridium acetobutylicum production of butanol using high-energy carbon heavy ion irradiation".ENGINEERING IN LIFE SCIENCES 18(2018):721-731.