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	Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus); Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)
	Xing Mingqing2,3; Sun Xiuqin1; Zheng Fengrong1; Qu Lingyun1; Hong Xuguang1; Wu Suqi1; Zheng Minggang1; Zhang Jinxing1
刊名	CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY ; CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
	2011-05 ; 2011-05
卷号	29期号:3页码:603-608
关键词	Japanese flounder Japanese flounder Paralichthys olivaceus Paralichthys olivaceus lymphocystis disease lymphocystis disease proteomics proteomics serum serum
ISSN号	0254-4059 ; 0254-4059
DOI	10.1007/s00343-011-0060-4 ; 10.1007/s00343-011-0060-4
英文摘要	To reveal the key factor in self-healing from LCDV (lymphocystis disease virus)-infected Japanese flounder (Paralichthys olivaceus), serum proteins from self-healing and sick Japanese flounder were separated by two-dimensional electrophoresis to screen differentially expressed proteins. Protein spots demonstrating changes greater than two-fold in the expression level were digested and further identified in capillary liquid chromatography tandem mass spectrometry (LC-MS/MS). Two immunity-relevant proteins were thus identified as transferrin and the complement component C3 of Japanese flounder. These findings suggest that the two proteins may play important roles in the self-healing of lymphocystis in Japanese flounder. This is an important theoretical foundation to promote self-healing in LCDV-infected Japanese flounder by improving their innate immunity.; To reveal the key factor in self-healing from LCDV (lymphocystis disease virus)-infected Japanese flounder (Paralichthys olivaceus), serum proteins from self-healing and sick Japanese flounder were separated by two-dimensional electrophoresis to screen differentially expressed proteins. Protein spots demonstrating changes greater than two-fold in the expression level were digested and further identified in capillary liquid chromatography tandem mass spectrometry (LC-MS/MS). Two immunity-relevant proteins were thus identified as transferrin and the complement component C3 of Japanese flounder. These findings suggest that the two proteins may play important roles in the self-healing of lymphocystis in Japanese flounder. This is an important theoretical foundation to promote self-healing in LCDV-infected Japanese flounder by improving their innate immunity.
资助项目	National High Technology Research and Development Program of China (863 program)[2006AA100309] ; National High Technology Research and Development Program of China (863 program)[2006AA100309]
WOS研究方向	Marine & Freshwater Biology ; Marine & Freshwater Biology ; Oceanography ; Oceanography
语种	英语 ; 英语
出版者	SCIENCE PRESS ; SCIENCE PRESS
WOS记录号	WOS:000292558100013 ; WOS:000292558100013
内容类型	期刊论文
源URL	[http://ir.fio.com.cn/handle/2SI8HI0U/4226]
专题	业务部门_海洋生态研究中心
作者单位	1.SOA, Inst Oceanog 1, Qingdao 266061, Peoples R China; 2.Ocean Univ China, Coll Marine Life Sci, Qingdao 266003, Peoples R China; 3.Qingdao Municipal Hosp, Dept Clin Lab, Qingdao 266011, Peoples R China
推荐引用方式 GB/T 7714	Xing Mingqing,Sun Xiuqin,Zheng Fengrong,et al. Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus), Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2011, 2011,29, 29(3):603-608, 603-608.
APA	Xing Mingqing.,Sun Xiuqin.,Zheng Fengrong.,Qu Lingyun.,Hong Xuguang.,...&Zhang Jinxing.(2011).Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus).CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,29(3),603-608.
MLA	Xing Mingqing,et al."Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 29.3(2011):603-608.

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