Self-Assembled Cell Microarray (SAMcell) for High-Throughput RNAi Screening

doi:10.1007/978-1-4939-6337-9_8

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	Self-Assembled Cell Microarray (SAMcell) for High-Throughput RNAi Screening
	Zhang Hanshuo ; Li Juan
刊名	Methods in molecular biology (Clifton, N.J.)
	2016
关键词	Cell behavior,Chip,High-throughput screening,RNAi,SAMcell
DOI	10.1007/978-1-4939-6337-9_8
英文摘要	RNAi has now become a valuable research tool for cell-based high-throughput screening. However, traditional RNAi high-throughput methods are based on multi-well plates, relying on expensive instruments and complicated operations. In this chapter, we describe a method termed self-assembled cell microarray (SAMcell), which integrates micro-fabrication, reverse transfection, and RNAi technologies and allows for cell behavior investigations to be performed directly on the cell chip. This method has been successfully employed to perform large-scale functional screening assays to identify gene modulators of cell migration, cell proliferation, and cellular apoptosis.; PubMed; 95-102; 1470
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/493051]
专题	工学院
推荐引用方式 GB/T 7714	Zhang Hanshuo,Li Juan. Self-Assembled Cell Microarray (SAMcell) for High-Throughput RNAi Screening[J]. Methods in molecular biology (Clifton, N.J.),2016.
APA	Zhang Hanshuo,&Li Juan.(2016).Self-Assembled Cell Microarray (SAMcell) for High-Throughput RNAi Screening.Methods in molecular biology (Clifton, N.J.).
MLA	Zhang Hanshuo,et al."Self-Assembled Cell Microarray (SAMcell) for High-Throughput RNAi Screening".Methods in molecular biology (Clifton, N.J.) (2016).