Reactive radical-driven bacterial inactivation by   hydrogen-peroxide-enhanced plasma-activated-water

doi:10.1140/epjst/e2016-60330-y

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	Reactive radical-driven bacterial inactivation by hydrogen-peroxide-enhanced plasma-activated-water
	Wu, Songjie ; Zhang, Qian ; Ma, Ruonan ; Yu, Shuang ; Wang, Kaile ; Zhang, Jue ; Fang, Jing
刊名	EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS
	2017
关键词	ATMOSPHERIC-PRESSURE PLASMA HYDROXYL RADICALS AQUEOUS-SOLUTION GENERATION ACID
DOI	10.1140/epjst/e2016-60330-y
英文摘要	The combined effects of plasma activated water (PAW) and hydrogen peroxide (H2O2), PAW/HP, in sterilization were investigated in this study. To assess the synergistic effects of PAW/HP, S. aureus was selected as the test microorganism to determine the inactivation efficacy. Also, the DNA/RNA and proteins released by the bacterial suspensions under different conditions were examined to confirm membrane integrity. Additionally, the intracellular pH (pH(i)) of S. aureus was measured in our study. Electron spin resonance spectroscopy (ESR) was employed to identify the presence of radicals. Finally, the oxidation reduction potential (ORP), conductivity and pH were measured. Our results revealed that the inactivation efficacy of PAW/HP is much greater than that of PAW, while increased H2O2 concentration result in higher inactivation potential. More importantly, as compared with PAW, the much stronger intensity ESR signals and higher ORP in PAW/HP suggests that the inactivation mechanism of the synergistic effects of PAW/HP: more reactive oxygen species (ROS) and reactive nitrogen species (RNS), especially OH and NO radicals, are generated in PAW combined with H2O2 resulting in more deaths of the bacteria.; Peking University Biomed-X Foundation; SCI(E); ARTICLE; 13; 2887-2899; 226
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/471822]
专题	工学院
推荐引用方式 GB/T 7714	Wu, Songjie,Zhang, Qian,Ma, Ruonan,et al. Reactive radical-driven bacterial inactivation by hydrogen-peroxide-enhanced plasma-activated-water[J]. EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS,2017.
APA	Wu, Songjie.,Zhang, Qian.,Ma, Ruonan.,Yu, Shuang.,Wang, Kaile.,...&Fang, Jing.(2017).Reactive radical-driven bacterial inactivation by hydrogen-peroxide-enhanced plasma-activated-water.EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS.
MLA	Wu, Songjie,et al."Reactive radical-driven bacterial inactivation by hydrogen-peroxide-enhanced plasma-activated-water".EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS (2017).