Atomic layer deposited ZrO2 nanofilm on Mg-Sr alloy for enhanced   corrosion resistance and biocompatibility

doi:10.1016/j.actbio.2017.06.015

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	Atomic layer deposited ZrO2 nanofilm on Mg-Sr alloy for enhanced corrosion resistance and biocompatibility
	Yang, Qiuyue ; Yuan, Wei ; Liu, Xiangmei ; Zheng, Yufeng ; Cui, Zhenduo ; Yang, Xianjin ; Pan, Haobo ; Wu, Shuilin
刊名	ACTA BIOMATERIALIA
	2017
关键词	Magnesium alloy Biodegradability Corrosion Nanofilms Atomic layer deposition PLASMA ELECTROLYTIC OXIDATION BIODEGRADABLE MAGNESIUM ALLOYS IN-VITRO CORROSION ORTHOPEDIC IMPLANTS BEHAVIOR SURFACE BONE DEGRADATION COATINGS STRONTIUM
DOI	10.1016/j.actbio.2017.06.015
英文摘要	The biodegradability and good mechanical property of magnesium alloys make them potential biomedical materials. However, their rapid corrosion rate in the human body's environment impairs these advantages and limits their clinical use. In this work, a compact zirconia (ZrO2) nanofilm was fabricated on the surface of a magnesium-strontium (Mg-Sr) alloy by the atomic layer deposition (ALD) method, which can regulate the thickness of the film precisely and thus also control the corrosion rate. Corrosion tests reveal that the ZrO2 film can effectively reduce the corrosion rate of Mg-Sr alloys that is closely related to the thickness of the film. The cell culture test shows that this kind of ZrO2 film can also enhance the activity and adhesion of osteoblasts on the surfaces of Mg-Sr alloys. Statement of Significance The significance of the current work is to develop a zirconia nanofilm on biomedical MgSr alloy with controllable thickness precisely through atomic layer deposition technique. By adjusting the thickness of nanofilm, the corrosion rate of Mg-Sr alloy can be modulated, thereafter, the degradation rate of Mg based alloys can be controlled precisely according to actual clinical requirement. In addition, this zirconia nanofilm modified Mg-Sr alloys show excellent biocompatibility than the bare samples. Hence, this work provides a new surface strategy to control the degradation rate while improving the biocompatibility of substrates. (C) 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.; National Natural Science Foundation of China [51422102, 51671081]; National Key Research and Development Program of China [2016YFC1100600, 2016YFC1100604]; Shenzhen Peacock Program [1108110035863317]; SCI(E); ARTICLE; 515-526; 58
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/471729]
专题	工学院
推荐引用方式 GB/T 7714	Yang, Qiuyue,Yuan, Wei,Liu, Xiangmei,et al. Atomic layer deposited ZrO2 nanofilm on Mg-Sr alloy for enhanced corrosion resistance and biocompatibility[J]. ACTA BIOMATERIALIA,2017.
APA	Yang, Qiuyue.,Yuan, Wei.,Liu, Xiangmei.,Zheng, Yufeng.,Cui, Zhenduo.,...&Wu, Shuilin.(2017).Atomic layer deposited ZrO2 nanofilm on Mg-Sr alloy for enhanced corrosion resistance and biocompatibility.ACTA BIOMATERIALIA.
MLA	Yang, Qiuyue,et al."Atomic layer deposited ZrO2 nanofilm on Mg-Sr alloy for enhanced corrosion resistance and biocompatibility".ACTA BIOMATERIALIA (2017).