In vitro studies on silver implanted pure iron by metal vapor vacuum arc   technique

doi:10.1016/j.colsurfb.2016.01.065

CORC > 北京大学 > 工学院

	In vitro studies on silver implanted pure iron by metal vapor vacuum arc technique
	Huang, Tao ; Cheng, Yan ; Zheng, Yufeng
刊名	COLLOIDS AND SURFACES B-BIOINTERFACES
	2016
关键词	Pure iron Silver ion implantation Corrosion Biocompatibility FE-BASED ALLOYS STENTS BIOCOMPATIBILITY DEGRADATION CYTOTOXICITY COMPOSITES NANOPARTICLES BIOMATERIALS CORROSION SURFACE
DOI	10.1016/j.colsurfb.2016.01.065
英文摘要	Pure iron has been verified as a promising biodegradable metal for absorbable cardiovascular stent usage. However, the degradation rate of pure iron is too slow. To accelerate the degradation of the surface of pure iron, silver ions were implanted into pure iron by metal vapor vacuum arc (MEVVA) source at an extracted voltage of 40 keV. The implanted influence was up to 2 x 10(17) ions/cm(2). The composition and depth profiles, corrosion behavior and biocompatibility of Ag ion implanted pure iron were investigated. The implantation depths of Ag was around 60 nm. The element Ag existed as Ag2O in the outermost layer, then gradually transited to metal atoms in zero valent state with depth increase. The implantation of Ag ions accelerated the corrosion rate of pure iron matrix, and exhibited much more uniform corrosion behavior. For cytotoxicity assessment, the implantation of Ag ions slightly decreased the viability of all kinds of cell lines used in these tests. The hemolysis rate of Ag ion implanted pure iron was lower than 2%, which was acceptable, whereas the platelet adhesion tests indicated the implantation of Ag ions might increase the risk of thrombosis. (C) 2016 Elsevier B.V. All rights reserved.; National Basic Research Program of China (973 Program) [2012CB619102, 2012CB619100]; National Science Fund for Distinguished Young Scholars [51225101]; National Natural Science Foundation of China [51431002, 31170909]; NSFC/RGC Joint Research Scheme [51361165101]; State Key Laboratory for Mechanical Behavior of Materials [20141615]; Beijing Municipal Science and Technology Project [Z141100002814008]; SCI(E); EI; PubMed; ARTICLE; yfzheng@pku.edu.cn; 20-29; 142
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/434705]
专题	工学院
推荐引用方式 GB/T 7714	Huang, Tao,Cheng, Yan,Zheng, Yufeng. In vitro studies on silver implanted pure iron by metal vapor vacuum arc technique[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2016.
APA	Huang, Tao,Cheng, Yan,&Zheng, Yufeng.(2016).In vitro studies on silver implanted pure iron by metal vapor vacuum arc technique.COLLOIDS AND SURFACES B-BIOINTERFACES.
MLA	Huang, Tao,et al."In vitro studies on silver implanted pure iron by metal vapor vacuum arc technique".COLLOIDS AND SURFACES B-BIOINTERFACES (2016).