Simultaneous production of triacylglycerol and high-value carotenoids by   the astaxanthin-producing oleaginous green microalga Chlorella   zofingiensis

doi:10.1016/j.biortech.2016.04.112

CORC > 北京大学 > 工学院

	Simultaneous production of triacylglycerol and high-value carotenoids by the astaxanthin-producing oleaginous green microalga Chlorella zofingiensis
	Liu, Jin ; Mao, Xuemei ; Zhou, Wenguang ; Guarnieri, Michael T.
刊名	BIORESOURCE TECHNOLOGY
	2016
关键词	Astaxanthin Biofuels Chlorella zofingiensis Integrated production Stress conditions Triacylglycerol HAEMATOCOCCUS-PLUVIALIS OUTDOOR CULTIVATION LIPID PRODUCTIVITY DESATURASE GENE OPEN POND ACCUMULATION BIODIESEL PHOTOBIOREACTOR VULGARIS STRAINS
DOI	10.1016/j.biortech.2016.04.112
英文摘要	The production of lipids and astaxanthin, a high-value carotenoid, by Chlorella zofingiensis was investigated under different culture conditions. Comparative analysis revealed a good correlation between triacylglycerol (TAG) and astaxanthin accumulation in C. zofingiensis. Stress conditions promoted cell size and weight and induced the accumulation of neutral lipids, especially TAG and astaxanthin, with a concomitant decrease in membrane lipids. The highest contents of TAG and astaxanthin achieved were 387 and 4.89 mg g(-1) dry weight, respectively. A semi-continuous culture strategy was developed to optimize the TAG and astaxanthin productivities, which reached 297 and 3.3 mg L-1 day(-1), respectively. Additionally, astaxanthin accumulation was enhanced by inhibiting de novo fatty acid biosynthesis. In summary, our study represents a pioneering work of utilizing Chlorella for the integrated production of lipids and high-value products and C. zofingiensis has great potential to be a promising production strain and serve as an emerging oleaginous model alga. (C) 2016 Elsevier Ltd. All rights reserved.; National Natural Science Foundation of China [31571807]; start-up grant from National Youth Thousand Talents Program; 985 Project of Peking University; SCI(E); EI; PubMed; ARTICLE; gjinliu@pku.edu.cn; 319-327; 214
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/433835]
专题	工学院
推荐引用方式 GB/T 7714	Liu, Jin,Mao, Xuemei,Zhou, Wenguang,et al. Simultaneous production of triacylglycerol and high-value carotenoids by the astaxanthin-producing oleaginous green microalga Chlorella zofingiensis[J]. BIORESOURCE TECHNOLOGY,2016.
APA	Liu, Jin,Mao, Xuemei,Zhou, Wenguang,&Guarnieri, Michael T..(2016).Simultaneous production of triacylglycerol and high-value carotenoids by the astaxanthin-producing oleaginous green microalga Chlorella zofingiensis.BIORESOURCE TECHNOLOGY.
MLA	Liu, Jin,et al."Simultaneous production of triacylglycerol and high-value carotenoids by the astaxanthin-producing oleaginous green microalga Chlorella zofingiensis".BIORESOURCE TECHNOLOGY (2016).