Multiple stimuli-responsive polymeric micelles for controlled release | |
Dong, Jie ; Wang, Yani ; Zhang, Jian ; Zhan, Xiaowei ; Zhu, Siquan ; Yang, Huai ; Wang, Guojie | |
刊名 | 软性材料 |
2013 | |
关键词 | BLOCK-COPOLYMER MICELLES GENE DELIVERY SHELL NANOPARTICLES ASSEMBLIES AZOBENZENE VESICLES CORE DRUG ATRP |
DOI | 10.1039/c2sm27116h |
英文摘要 | Multiple stimuli-responsive polymeric micelles that can respond to light, temperature and pH have been prepared by a novel polymer, pyrene-functionalized poly (dimethylaminoethyl methacrylate), where the pyrene-quaternized segments form a light-responsive shell and the unquaternized segments form a temperature/pH-responsive core. Under UV irradiation, the micelles could be dissociated; when the temperature increased above the lower critical solution temperature, the micelles shrunk. At pH 3, the micelles could be swelled/dissociated and at pH 10, the micelles could be collapsed to complex micelles. The controlled release of Nile Red from the micelle under stimuli was demonstrated. This novel multiple stimuli-responsive micelle shows potential as a new nanocarrier and delivery system.; Chemistry, Physical; Materials Science, Multidisciplinary; Physics, Multidisciplinary; Polymer Science; SCI(E); EI; 28; ARTICLE; 2; 370-373; 9 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/228285] |
专题 | 工学院 |
推荐引用方式 GB/T 7714 | Dong, Jie,Wang, Yani,Zhang, Jian,et al. Multiple stimuli-responsive polymeric micelles for controlled release[J]. 软性材料,2013. |
APA | Dong, Jie.,Wang, Yani.,Zhang, Jian.,Zhan, Xiaowei.,Zhu, Siquan.,...&Wang, Guojie.(2013).Multiple stimuli-responsive polymeric micelles for controlled release.软性材料. |
MLA | Dong, Jie,et al."Multiple stimuli-responsive polymeric micelles for controlled release".软性材料 (2013). |
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