Microstructure, mechanical property, bio-corrosion and cytotoxicity   evaluations of Mg/HA composites

doi:10.1016/j.msec.2010.03.016

CORC > 北京大学 > 工学院

	Microstructure, mechanical property, bio-corrosion and cytotoxicity evaluations of Mg/HA composites
	Gu, Xuenan ; Zhou, Weirui ; Zheng, Yufeng ; Dong, Limin ; Xi, Yulin ; Chai, Donglang
刊名	materials science engineering c materials for biological applications
	2010
关键词	Mg/HA composite Microstructure Mechanical property Corrosion Cytotoxicity MAGNESIUM MATRIX COMPOSITE IN-VIVO CORROSION ALLOYS BONE VITRO BIOACTIVITY
DOI	10.1016/j.msec.2010.03.016
英文摘要	Mg/HA (10 wt.%, 20 wt.% and 30 wt.%) composites were prepared by pure magnesium and hydroxyapatite (HA) powders using powder metallurgy (PM) method. The microstructure, mechanical property, corrosion and cytotoxicity of these Mg/HA composites were studied, with the bulk pure magnesium as control. The results showed that the main constitutional phases of Mg/HA composites were simply alpha-Mg and HA. The HA particulates distributed uniformly in Mg matrix for Mg/10HA composite, and few HA clustering occasionally spread over the Mg/20HA composite, whereas severe agglomeration of HA particulates could be seen for Mg/30HA composite. The yield tensile strength of Mg/10HA composite increased compared with that of the as-extruded bulk pure magnesium, yet the yield tensile strength, ultimate tensile strength and ductility of Mg/HA composites decreased with the further increase of HA content. The corrosion rate of Mg/HA composites increased with the increment of HA content. The cytotoxicity tests indicated that Mg/10HA extract showed no toxicity to L-929 cells, whereas Mg/20HA and Mg/30HA composite extracts induced significantly reduced cell viability. (C) 2010 Elsevier B.V. All rights reserved.; Materials Science, Biomaterials; SCI(E); EI; 26; ARTICLE; 6; 827-832; 30
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/154870]
专题	工学院
推荐引用方式 GB/T 7714	Gu, Xuenan,Zhou, Weirui,Zheng, Yufeng,et al. Microstructure, mechanical property, bio-corrosion and cytotoxicity evaluations of Mg/HA composites[J]. materials science engineering c materials for biological applications,2010.
APA	Gu, Xuenan,Zhou, Weirui,Zheng, Yufeng,Dong, Limin,Xi, Yulin,&Chai, Donglang.(2010).Microstructure, mechanical property, bio-corrosion and cytotoxicity evaluations of Mg/HA composites.materials science engineering c materials for biological applications.
MLA	Gu, Xuenan,et al."Microstructure, mechanical property, bio-corrosion and cytotoxicity evaluations of Mg/HA composites".materials science engineering c materials for biological applications (2010).