Mass transport in solid tumors (II) - Drug delivery | |
Lei, XX ; Wu, WY ; Wen, GB ; Chen, JG | |
刊名 | applied mathematics and mechanics english edition
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1998 | |
关键词 | MACROMOLECULES FLUID |
英文摘要 | Based on the flow field solution of the three-porous-medium model for tumor microcirculation, the diffusion-convection equations are solved with various initial and boundary conditions using finite element method. The concentration profile of two therapeutic agents: immunoglobulin G (IgG) and its antigen-binding fragment (Fab) in blood, lymph and interstitial fluid are obtained for normal-tissue-surrounded tumor. The effect of tumor microvasculature, lymph function, drug injection mode, the molecular weight and binding kinetics of the drug on the distribution in tumors are also considered.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000078983400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Mathematics, Applied; Mechanics; SCI(E); EI; 0; ARTICLE; 12; 1151-1160; 19 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/154318] ![]() |
专题 | 工学院 |
推荐引用方式 GB/T 7714 | Lei, XX,Wu, WY,Wen, GB,et al. Mass transport in solid tumors (II) - Drug delivery[J]. applied mathematics and mechanics english edition,1998. |
APA | Lei, XX,Wu, WY,Wen, GB,&Chen, JG.(1998).Mass transport in solid tumors (II) - Drug delivery.applied mathematics and mechanics english edition. |
MLA | Lei, XX,et al."Mass transport in solid tumors (II) - Drug delivery".applied mathematics and mechanics english edition (1998). |
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