Long-duration transcutaneous electric acupoint stimulation alters   small-world brain functional networks

doi:10.1016/j.mri.2013.01.006

CORC > 北京大学 > 工学院

	Long-duration transcutaneous electric acupoint stimulation alters small-world brain functional networks
	Zhang, Yue ; Jiang, Yin ; Glielmi, Christopher B. ; Li, Longchuan ; Hu, Xiaoping ; Wang, Xiaoying ; Han, Jisheng ; Zhang, Jue ; Cui, Cailian ; Fang, Jing
刊名	磁共振成像
	2013
关键词	Small-world Brain functional networks Resting-state fMRI Long-duration transcutaneous electric acupoint stimulation (TEAS) ORBITOFRONTAL CORTEX AFFECTIVE DIMENSION ACUPUNCTURE FMRI PAIN CONNECTIVITY MECHANISMS FREQUENCY PERFUSION SCHIZOPHRENIA
DOI	10.1016/j.mri.2013.01.006
英文摘要	Acupuncture, which is recognized as an alternative and complementary treatment in Western medicine, has long shown efficiencies in chronic pain relief, drug addiction treatment, stroke rehabilitation and other clinical practices. The neural mechanism underlying acupuncture, however, is still unclear. Many studies have focused on the sustained effects of acupuncture on healthy subjects, yet there are very few on the topological organization of functional networks in the whole brain in response to long-duration acupuncture (longer than 20 min). This paper presents a novel study on the effects of long-duration transcutaneous electric acupoint stimulation (TEAS) on the small-world properties of brain functional networks. Functional magnetic resonance imaging was used to construct brain functional networks of 18 healthy subjects (9 males and 9 females) during the resting state. All subjects received both TEAS and minimal TEAS (MTEAS) and were scanned before and after each stimulation. An altered functional network was found with lower local efficiency and no significant change in global efficiency for healthy subjects after TEAS, while no significant difference was observed after MTEAS. The experiments also showed that the nodal efficiencies in several paralimbic/limbic regions were altered by TEAS, and those in middle frontal gyrus and other regions by MTEAS. To remove the psychological effects and the baseline, we compared the difference between diffTEAS (difference between after and before TEAS) and diffMTEAS (difference between after and before MTEAS). The results showed that the local efficiency was decreased and that the nodal efficiencies in frontal gyrus, orbitofrontal cortex, anterior cingulate gyrus and hippocampus gyrus were changed. Based on those observations, we conclude that long-duration TEAS may modulate the short-range connections of brain functional networks and also the limbic system. (c) 2013 Elsevier Inc. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000322944600010&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Radiology, Nuclear Medicine & Medical Imaging; SCI(E); PubMed; 5; ARTICLE; 7; 1105-1111; 31
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/153892]
专题	工学院
推荐引用方式 GB/T 7714	Zhang, Yue,Jiang, Yin,Glielmi, Christopher B.,et al. Long-duration transcutaneous electric acupoint stimulation alters small-world brain functional networks[J]. 磁共振成像,2013.
APA	Zhang, Yue.,Jiang, Yin.,Glielmi, Christopher B..,Li, Longchuan.,Hu, Xiaoping.,...&Fang, Jing.(2013).Long-duration transcutaneous electric acupoint stimulation alters small-world brain functional networks.磁共振成像.
MLA	Zhang, Yue,et al."Long-duration transcutaneous electric acupoint stimulation alters small-world brain functional networks".磁共振成像 (2013).